Evidence map›Paper›PMID 41255901›Full record

ReviewJournal of clinical practice and research2024

A Comprehensive Analysis of the Efficacy of Injectable Medications in Relieving Temporomandibular Joint Discomfort: A Systematic Review.

Ghassan Darwish

Abstract readReview
In one paragraph

Review in Journal of clinical practice and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ghassan DarwishDepartment of Oral and Maxillofacial Surgery, College of Dentistry, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Temporomandibular joint (TMJ) discomfort is a prevalent condition affecting a significant portion of the global population, often leading to impaired quality of life and reduced oral functionality. Various treatment modalities have been explored to alleviate TMJ discomfort, with injectable medications emerging as a promising therapeutic approach. This systematic review aims to provide a comprehensive overview of the efficacy of injectable medications in relieving TMJ discomfort. A rigorous search of electronic databases was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The findings are presented in a narrative synthesis, highlighting trends in treatment outcomes and potential complications associated with injectable medications for TMJ discomfort. The Risk-of-bias VISualization (Robvis) and the Mixed Methods Appraisal Tool (MMAT) were used as quality assessment tools. This review synthesizes valuable insights from the scientific literature across multiple electronic databases. A total of 25 articles were selected for inclusion in the study. Most patients investigated had been diagnosed with internal derangement of the TMJ. Various injections, including Sodium Hyaluronate (SH), Autologous Blood Injection (ABI), Platelet-Rich Plasma (PRP), and Corticosteroid (CS), were administered to alleviate pain and discomfort. Most studies administered these injections after arthrocentesis or in combination with other injections. The combination of arthrocentesis with additional injections demonstrated superior outcomes compared to the sole use of a single injection. This review underscores the need for further research to optimize the selection and administration of injectable medications for Temporomandibular disorders management. It also emphasizes the importance of a personalized approach, considering individual patient characteristics and preferences in treatment decision-making.

Indexed as

injectable medications for TMJ discomfortmedications for TMJ discomfortTemporomandibular joint pain reliefTMJ discomfortTMJ pain

Identifiers

PMID41255901
PMCPMC12478756

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.