Evidence map›Paper›PMID 41255790›Full record

ArticleFrontiers in neurology2025

NP-guide: a portable projection-based navigation system for neurosurgery and beyond.

Zhongjie Shi, Xin Gao, Sifang Chen, Deyong Xiao, Zhangyu Li, Xiaojun Li, Yilong Peng, Jiajia Yu, Zhanxiang Wang

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In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Zhongjie Shi *Department of Neurosurgery, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Xin Gao *Department of Neurosurgery, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Sifang ChenDepartment of Neurosurgery, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Deyong XiaoDepartment of Neurosurgery, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Zhangyu LiDepartment of Neurosurgery, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Xiaojun LiDepartment of Neurosurgery, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Yilong PengDepartment of Neurosurgery, Jiangmen Central Hospital, Jiangmen, China.
Jiajia YuCollege of Electronics and Information Engineering, Wuyi University, Jiangmen, China.
Zhanxiang WangDepartment of Neurosurgery, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Stereotactic systems and various robot-assisted navigation platforms in neurosurgery have enabled high-precision localization. However, these systems, while highly accurate, are expensive, technically demanding, and procedurally complex, making them less practical for routine use. This study introduced and evaluated the Navigation and Projection Guide (NP-Guide), a projection-based augmented reality (AR) system designed to provide a portable and accessible solution for surgical navigation. Methods: NP-Guide, a mobile application, projects patient imaging data and three-dimensional (3D) reconstructions onto the patient's head surface to assist with localization. This proof-of-concept study prospectively enrolled 52 neurosurgical patients, randomized to the NP-Guide group ( Results: Baseline characteristics were comparable (all Conclusion: The NP-Guide demonstrated accurate, efficient, and reproducible projection-based localization in this proof-of-concept study. Its portability, low cost, and ease of use suggest potential value, particularly in resource-limited settings. However, these findings should be interpreted as preliminary, and further phantom experiments and multicenter clinical studies are required before widespread adoption in routine practice.

Indexed as

augmented realityneurosurgeryNP-guideproof-of-concept studysurgical navigation

Identifiers

PMID41255790
PMCPMC12620224

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