Evidence map›Paper›PMID 41255778›Full record

ArticleLaryngoscope investigative otolaryngology2025

Impact of Balance and Dizziness Problems on Falls in Older Adults: The Longitudinal AGES-Reykjavik Study.

Chuan-Ming Li, Howard J Hoffman, Bryan K Ward, Charles C Della Santina, Mary Frances Cotch, May S Chiu, Katalin G Losonczy, Christa L Themann, Lenore J Launer, Kristin Siggeirsdottir and 3 more

Abstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Hearing-Functioning Problems Across High-Burden Adult Health Conditions in Africa.International journal of environmental research and public health · 2026
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chuan-Ming LiEpidemiology, Statistics, and Population Sciences National Institute on Deafness and Other Communication Disorders, National Institutes of Health Bethesda Maryland USA.
Howard J HoffmanEpidemiology, Statistics, and Population Sciences National Institute on Deafness and Other Communication Disorders, National Institutes of Health Bethesda Maryland USA.ORCID https://orcid.org/0000-0003-4105-0808
Bryan K WardDepartment of Otolaryngology-Head and Neck Surgery Johns Hopkins University School of Medicine Baltimore Maryland USA.ORCID https://orcid.org/0000-0001-5201-6117
Charles C Della SantinaDepartment of Otolaryngology-Head and Neck Surgery Johns Hopkins University School of Medicine Baltimore Maryland USA.
Mary Frances CotchOffice of Vision Health and Population Sciences National Eye Institute, National Institutes of Health Bethesda Maryland USA.
May S ChiuEpidemiology, Statistics, and Population Sciences National Institute on Deafness and Other Communication Disorders, National Institutes of Health Bethesda Maryland USA.
Katalin G LosonczyStephenson and Stephenson, Research and Consulting (SASRAC), LLC Batavia Ohio USA.
Christa L ThemannDivision of Field Studies and Engineering National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention Cincinnati Ohio USA.
Lenore J LaunerLaboratory of Epidemiology and Population Sciences National Institute on Aging, National Institutes of Health Baltimore Maryland USA.
Kristin SiggeirsdottirIcelandic Heart Association Research Institute and Clinic Kopavogur Iceland.
Palmi V JonssonFaculty of Medicine University of Iceland Reykjavik Iceland.
Vilmundur GudnasonIcelandic Heart Association Research Institute and Clinic Kopavogur Iceland.
Hannes PetersenFaculty of Medicine University of Iceland Reykjavik Iceland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the impact of balance and dizziness problems (BDP) and other risk factors on falls in a longitudinal, population-based cohort of older adults. Methods: The Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-RS I) 2002-2006 examined 5764 adults aged 66-98. Five years later, 3316 surviving subjects were reexamined in AGES-RS II. Participants were asked about BDP, falls, usual activities, and health conditions. BDP symptoms during the past 12 months included: vertigo (spinning/moving sensation); floating/spacey sensation; light-headedness (no moving sensation); near fainting (presyncope) or fainting (syncope); blurred vision with head movement (oscillopsia); and feeling off-balance/unsteady. Clinical assessments included hand grip and leg strength plus steps and time to walk 6 m. Results: During the past 12 months in AGES-RS II, BDP prevalence was 40.1% (males 35.2%, females 43.7%) and the prevalence of falling was 23.0% (males 20.9%, females 24.8%). BDP increased steps and time to walk 6 m. BDP increased the risk of falls (adjusted prevalence ratio [PR] = 1.53; 95% confidence interval [CI]: 1.34-1.76 for AGES-RS I, PR = 1.77, 95% CI: 1.55-2.03 for AGES-RS II). The prevalence of ≥ 2 falls was 8.9% (15.6% with BDP vs. 4.4% without BDP). Among those who fell ≥ 2 times, 70.4% reported BDP in the past 12 months. Additional risk of falling was associated with fear/panic attacks, memory loss, hearing loss, and other health conditions. Conclusion: BDP are common in older adults and associated with 50% to 80% increased risk of falling and even greater risk of falling ≥ 2 times. Quantitative estimates are provided for contributing factors that further increase the risk of falls. Level of Evidence: 2 (prospective cohort study).

Indexed as

dizzinessfallsimbalancepopulation‐based longitudinal studyvertigo

Identifiers

PMID41255778
PMCPMC12620664

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.