ArticleWorld journal of clinical pediatrics2025
Comprehensive study of community acquired
Article in World journal of clinical pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- S100A8/A9 as a novel predictor for severe Mycoplasma pneumoniae pneumonia in children: A prospective observational study.Clinics (Sao Paulo, Brazil) · 2026Article
- Immunopathogenesis, molecular phenotyping, and host-directed interventions for severe pediatricFrontiers in cellular and infection microbiology · 2026Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background
aimTo perform the comprehensive study of community acquired MPP cases registered in 2023 in Baoding Hospital, China.
methodsA total of 1160 children from 1 month to 15 years old with confirmed MPP diagnosis were enrolled in the study. The blood and respiratory samples were collected within the 24 hours after admission. The hematological parameters, biochemical markers, cytokine profiles were assessed. The respiratory samples were tested for the presence of
resultsNumber of MPP cases has dramatically increased starting August with peak in November. SMPP and general MPP (GMPP) were identified in 264 and 896 of 1160 hospitalized children. The binary logistic regression analysis identified six [C-reactive protein (CRP), lactate dehydrogenase, procalcitonin, erythrocyte sedimentation rate, fibrin and fibrinogen degradation products (FDPs), D-dimer] and four (neutrophils, CRP, FDPs, prothrombin time) predictors of SMPP in age groups 2-5 years and 6-15 years, respectively. Children with SMPP showed significantly higher levels of cytokine interleukin (IL)-17F (2-5 years), and cytokines interferon-gamma, tumor necrosis factor-alpha, IL-10 (6-13 years). Concomitant viral/bacterial pathogens were determined in 24.3% and 28.0% cases of SMPP and GMPP. Among them,
conclusionSpecific MPP epidemiological pattern associated with lifting NPIs was revealed: Increase of hospitalized cases, prevalence of
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