Evidence map›Paper›PMID 41255568›Full record

ArticleNAR molecular medicine2024

Coordinated evolution of the SNORD115 and SNORD116 tandem repeats at the imprinted Prader-Willi/Angelman locus.

Mathilde Guibert, Hélène Marty-Capelle, Anne Robert, Bruno Charpentier, Stéphane Labialle

Abstract read
In one paragraph

Article in NAR molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mathilde GuibertMédecine infantile, Hôpital d'enfants, Brabois, F-54500 Vandœuvre-lès-Nancy, France.
Hélène Marty-CapelleUniversité de Lorraine, CNRS, IMoPA, F-54000 Nancy, France.
Anne RobertUniversité de Lorraine, CNRS, IMoPA, F-54000 Nancy, France.
Bruno CharpentierUniversité de Lorraine, CNRS, IMoPA, F-54000 Nancy, France.
Stéphane LabialleUniversité de Lorraine, CNRS, IMoPA, F-54000 Nancy, France.ORCID https://orcid.org/0000-0003-3660-5485

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Prader-Willi/Angelman syndrome (PWS/AS) locus is regulated by the epigenetic mechanism of parental genomic imprinting. This region holds two eutherian-specific, large tandem repeats of box C/D small nucleolar RNA (Snord) genes called SNORD115 and SNORD116, whose loss of paternal expression is key in the development of the PWS. Snords represent an ancient class of noncoding RNAs that typically direct the 2'-

Identifiers

PMID41255568
PMCPMC12429941

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.