Evidence map›Paper›PMID 41255566›Full record

ArticleNAR molecular medicine2024

Geno2pheno: recombination detection for HIV-1 and HEV subtypes.

Martin Pirkl, Joachim Büch, Georg Friedrich, Michael Böhm, Dan Turner, Olaf Degen, Rolf Kaiser, Thomas Lengauer

Abstract read
In one paragraph

Article in NAR molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martin PirklInstitute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50935 Cologne, Germany.ORCID https://orcid.org/0000-0002-6986-0813
Joachim BüchInstitute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50935 Cologne, Germany.ORCID https://orcid.org/0000-0003-3534-9512
Georg FriedrichMax Planck Institute for Informatics, Saarland Informatics Campus, 66123 Saarbrücken, Germany.
Michael BöhmInstitute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50935 Cologne, Germany.ORCID https://orcid.org/0000-0003-1208-8647
Dan TurnerCrusaid Kobler AIDS Center, Tel Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, 69978 Tel Aviv, Israel.
Olaf DegenOutpatient Center of UKE GmbH, Division of Infectious Diseases, University Medical Center Hamburg-Eppendorf (UKE), 20251 Hamburg, Germany.
Rolf KaiserInstitute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50935 Cologne, Germany.ORCID https://orcid.org/0000-0002-2640-2548
Thomas LengauerInstitute of Virology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50935 Cologne, Germany.ORCID https://orcid.org/0000-0003-3801-2640

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Even after three decades of antiretroviral therapy for HIV-1 (human immunodeficiency virus 1), therapy failure is a continual challenge. This is especially so if the viral variant is a recombinant of subtypes. Thus, improved diagnosis of recombined subtypes can help with the selection of therapy. We are using a new implementation of the previously published computational method

Identifiers

PMID41255566
PMCPMC12430010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.