ReviewCureus2025
The Evolution of In Vitro Fertilization Practices in Saudi Arabia: Historical Perspectives and Future Directions.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In vitro fertilization (IVF) has revolutionized assisted reproductive technologies (ART), profoundly transforming infertility treatment since its inception. This procedure involves fertilizing an egg with sperm in a controlled laboratory environment, aiming to transfer the resulting embryo into the uterus for a successful pregnancy. While facilitating innovations like preimplantation genetic testing to avoid genetic abnormalities, it addresses a number of issues that contribute to infertility, such as endometriosis, male factor infertility, blocked fallopian tubes, and unexplained infertility. The IVF process consists of several key steps: ovarian stimulation, egg retrieval, fertilization, embryo culture, and embryo transfer. Ovarian stimulation involves administering fertility medications to promote the development of multiple eggs, increasing the chances of viable embryos. Egg retrieval is performed using a minimally invasive technique, followed by fertilization through conventional insemination or intracytoplasmic sperm injection (ICSI), which is particularly beneficial in male infertility cases. While IVF offers significant hope, it also carries risks, such as ovarian hyperstimulation syndrome, multiple pregnancies, and potential long-term health implications for mothers and babies. Success rates vary widely based on factors like age and clinic expertise, typically declining after age 40. Ethical considerations surrounding IVF include the moral status of embryos and equitable access to treatment, necessitating scrutiny as the commercialization of IVF can impose financial burdens on couples. This review will explore the evolution of IVF in Saudi Arabia, highlighting significant developments, challenges, and future research opportunities in this vital area of reproductive health. By addressing both technical and ethical dimensions, we aim to provide a comprehensive understanding of IVF's impact and potential in the region.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.