Evidence map›Paper›PMID 41255489›Full record

ReviewJournal of cardiovascular and thoracic research2025

Aspirin loading in coronary artery disease patients already taking aspirin: A systematic review.

Hila Asham, Ahmad Separham, Mohammad Javad Kamali, Musab Hama Faraj, Mehdi Maleki, Maryam Mehrpooya, Parvin Sarbakhsh, Taher Entezari-Maleki

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of cardiovascular and thoracic research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hila AshamDepartment of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0009-0003-5915-4805
Ahmad SeparhamCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad Javad KamaliDepartment of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Musab Hama FarajDepartment of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Mehdi MalekiCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Maryam MehrpooyaDepartment of Clinical Pharmacy, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.
Parvin SarbakhshDepartment of Statistics and Epidemiology, Faculty of Public Health, Tabriz University of Medical Sciences, Tabriz, Iran.
Taher Entezari-MalekiDepartment of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0003-3653-3653

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspirin is considered a cornerstone medication among patients with established coronary artery disease (CAD). There is a lack of evidence regarding aspirin reloading in CAD patients who are already receiving aspirin therapy. We performed this systematic review to address this gap of knowledge. A systematic review on PubMed, Embase, and the Cochrane Library was conducted from inception until July 15, 2024. Two authors independently performed study selection, data extraction, and risk of bias assessment. Means differences (MD) were used in a meta-analysis of related outcomes from the studies. Our review included four studies enrolling 1187 individuals with CAD and chronic aspirin use before admission. The results of this systematic review found that aspirin reloading is significantly associated with a reduction of thromboxane B

Indexed as

AspirinCoronary artery diseasesPercutaneous coronary interventionReloadingThromboxane B2

Identifiers

PMID41255489
PMCPMC12620139

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.