ArticleJournal of cardiovascular and thoracic research2025
Effect of sevoflurane on hemodynamic response during cardiopulmonary bypass in cardiac surgery patients: A randomized controlled trial.
Article in Journal of cardiovascular and thoracic research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Volatile Anesthesia in Contemporary Cardiac Surgery: Clinical Implications, Organ Protection and Perspectives for Personalized Perioperative Care.Journal of personalized medicine · 2026Review
- Evaluation of airway stress response and respiratory complications in adults undergoing general anesthesia with sevoflurane plus mivacurium chloride and positive pressure ventilation via laryngeal mask.American journal of translational research · 2026Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
Introduction: Sevoflurane has little effect on hemodynamics and has been shown to have a hemodynamic stabilizing effect in the pre- and post-cardiopulmonary bypass (CPB) period in patients undergoing cardiac surgery. However, clinical data on the effect of sevoflurane on the hemodynamic response during CPB in patients undergoing cardiac surgery are lacking. This study investigated whether the hemodynamic stabilizing effect of sevoflurane is demonstrated during CPB time in cardiac surgery patients. Methods: Fifty-five patients undergoing cardiac surgery under CPB were randomly assigned to anesthesia with sevoflurane (intervention group) or propofol (control group) during CPB. The primary outcomes were changes in hemodynamic parameters and the need for inotropes and vasopressors during CPB. Secondary outcomes were morbidity and mortality within 30 days after surgery. Results: The mean arterial pressure (MAP) at 5 minutes after heartbeat recovery and the end of CPB as well as central venous oxygen saturation (ScvO Conclusion: In conclusion, in patients undergoing cardiac surgery under CPB, the use of sevoflurane for anesthesia during CPB results in hemodynamic stability with less need for inotropes and vasopressors during CPB but morbidity and mortality within 30 days after surgery were not significantly different when compared with the control group.
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