Evidence map›Paper›PMID 41255427›Full record

ArticleAfrican journal of thoracic and critical care medicine2025

Evaluation and determinants of asthma control among adult patients with asthma attending the Johannesburg academic respiratory clinics: A cross-sectional study.

G J Titus, J Clark-Buchner, J Coetzee, Y Mbule, S Moodley, V Nephalama, T Seroka, T Stransky, L Wagener, A Graham and 2 more

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Article in African journal of thoracic and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

G J TitusSchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-5886-769X
J Clark-BuchnerSchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
J CoetzeeSchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Y MbuleSchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
S MoodleySchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
V NephalamaSchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
T SerokaSchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
T StranskySchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
L WagenerSchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
A GrahamSchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-5919-9742
M L WongSchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0001-7178-7953
E J ShaddockSchool of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0003-0182-9737

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The prevalence of asthma in South Africa is among the highest in Africa, but little research has been done regarding levels of asthma control and associated determinants. Objectives: To explore level of asthma control and perceived risk factors associated with poor control in adult patients with asthma attending respiratory clinics at three major hospitals in Johannesburg. Methods: This was a quantitative, descriptive, cross-sectional study of all adult patients attending the clinics. Participants were given a three-section self-reporting survey, consisting of a demographic section, an Asthma Control Test (ACT) questionnaire, and an eight-item Morisky Medication Adherence Scale (MMAS-8) questionnaire. Results: The prevalence of poor asthma control based on participants' ACT scores in this study was 71.3%. A significant linear regression was identified between the ACT and MMAS-8 scores in the uncontrolled asthma group. Significant associations between asthma control and the sociodemographic factors age, body mass index ≥25 and previous hospitalisation for exacerbation were found. No such associations existed for gender or level of education. In evaluating comorbidities, no significant association was found for hypertension, gastro-oesophageal reflux disease, sinusitis or diabetes mellitus. Of the patients, 89.3% used short-acting beta-agonists and 93.3% inhaled corticosteroids (ICSs); 58.7% were on combined long-acting beta-agonists and ICSs. Conclusion: Asthma control in the study setting was poor. There was also an interesting inverse relationship between control and therapy adherence. Further research is needed to better understand the issues surrounding asthma control and to lay the groundwork for policies to benefit asthma patients in the future. Study synopsis:

Indexed as

AsthmacontrolJohannesburgpublic sector

Identifiers

PMID41255427
PMCPMC12622878

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.