Low-Grade Myofibroblastic Sarcoma of the tongue: A case report and literature review.

Evangelos Kalfarentzos, Venetia Louka, Charalampos Gkilas, Nikolaos Katsoulas, Penelope Korkolopoulou, Nikolaos Kolomvos

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Article in Journal of clinical and experimental dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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5 · Who and what money

Authors and funding

6 authors.

Evangelos KalfarentzosDDS, MD, PhD, Assistant Professor OMFS, University of Athens Dental School, Department of Oral and Maxillofacial Surgery, "Evaggelismos" General Hospital, Athens, Greece.

Venetia LoukaDDS, Associate, School of Dentistry, National and Kapodistrian University of Athens, Greece.

Charalampos GkilasDDS, MSc, Private Dental Practice, Athens, Greece.

Nikolaos KatsoulasDDS, MD, MSc, Pathologist, 1st Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, Greece.

Penelope KorkolopoulouMD, PhD, Professor, 1st Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, Greece.

Nikolaos KolomvosDDS, MSc, PhD, MD, Assistant Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, National and Kapodistrian University of Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low-grade myofibroblastic sarcoma (LGMS) is an extremely rare mesenchymal neoplasm. It arises from the differentiation of myofibroblasts and demonstrates a preference for the head and neck region. Herein, we present a case of LGMS in a 52-year-old man with painless swelling in the anterior right area of the tongue. Histologically, the lesion consisted of spindle-shaped cells exhibiting mild to moderate nuclear atypia, arranged in fascicles with a storiform pattern. Neoplastic cells were positive for SMA and negative for EMA, CD34, h-caldesmon, desmin, β-catenin, S100, SOX10, and NF, with a Ki-67 index of 15-20%. Complete surgical excision with clear margins was the treatment of choice. Very few cases of LGMS have been documented in the literature, and regular follow-up for these patients is essential for drawing reliable conclusions regarding local recurrence and the metastatic potential of this tumor.

Identifiers

PMID41255404

DOI10.4317/jced.63065

PMCPMC12620985

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