Evidence map›Paper›PMID 41255166›Full record

ArticleMicrosurgery2025

Hybrid Total Achilles Tendon Reconstruction Combining Acellular Dermal Matrix Placement and Free Latissimus Dorsi Flap Coverage: A Report of Two Cases.

Beniamino Brunetti, Chiara Camilloni, Matteo Pazzaglia, Valeria Petrucci, Marco Morelli Coppola, Rosa Salzillo, Stefania Tenna, Irene Giovanna Aprile, Marco Germanotta, Sergio Valeri and 2 more

Abstract readCase Reports
In one paragraph

Article in Microsurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Beniamino BrunettiOperative Research Unit of Plastic, Reconstructive and Aesthetic Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Chiara CamilloniOperative Research Unit of Plastic, Reconstructive and Aesthetic Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Matteo PazzagliaOperative Research Unit of Plastic, Reconstructive and Aesthetic Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Valeria PetrucciResearch Unit of Plastic Surgery, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.ORCID 0000-0002-4500-7447
Marco Morelli CoppolaOperative Research Unit of Plastic, Reconstructive and Aesthetic Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.ORCID 0000-0002-8910-6586
Rosa SalzilloOperative Research Unit of Plastic, Reconstructive and Aesthetic Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Stefania TennaOperative Research Unit of Plastic, Reconstructive and Aesthetic Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Irene Giovanna AprileIRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.
Marco GermanottaIRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.
Sergio ValeriOperative Research Unit of Soft-Tissue Sarcomas Surgery Department, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Mauro BaroneOperative Research Unit of Plastic, Reconstructive and Aesthetic Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Paolo PersichettiOperative Research Unit of Plastic, Reconstructive and Aesthetic Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reconstruction of complex Achilles tendon defects involving both the tendon and the overlying soft tissues represents a challenging scenario for plastic surgeons. In this report, we present an innovative technique of hybrid total Achilles tendon reconstruction combining acellular dermal matrix placement to restore the full-thickness continuity of the tendon and free latissimus dorsi (LD) flap coverage to allow graft integration and simultaneously resurface the soft tissue defect, ultimately leading to lower limb salvage. Between August 2023 and February 2024 two patients received microsurgical hybrid reconstruction of complex defects, measuring 10 × 10 cm and 17 × 14 cm, respectively, involving the lower third of the leg and the Achilles tendon region, due to trauma with multiple previous failed surgeries and sarcoma resection. The full-thickness continuity of the tendon was reconstructed by use of an XCM BIOLOGIC Tissue Matrix (DePuy Synthes, Johnson & Johnson), measuring 6 and 10 cm long, respectively, folded in a three-layered tridimensional structure to recreate the shape and function of a new tendon. Subsequently, a free myo-cutaneous LD flap, was used to wrap and revascularize the neo-tendon and resurface the soft tissue defect. In both patients the flaps healed uneventfully, and neo-tendon integration was documented by MRI examination. The follow-up was uneventful. Long-term functional evaluation showed almost normal tendon excursion with both patients walking without assistance. The proposed hybrid approach may be a good alternative and innovative solution for the reconstruction of complex Achilles tendon defects consequent to trauma or oncological resection. Such results are more than promising for future studies on large series of patients.

Indexed as

Acellular DermisAchilles TendonFree Tissue FlapsPlastic Surgery ProceduresSuperficial Back MusclesTendon InjuriesAged, 80 and overFemaleHumansMaleMicrosurgeryMiddle AgedAchilles tendonfree flapmicrosurgeryregenerative medicinerepair

Identifiers

PMID41255166
PMCPMC12628040

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.