ArticlePain management2026
Patient-centered outcomes in the acute treatment of migraine: a prospective, real-world, longitudinal survey study (UNIVERSE II) comparing migraine patients who switch from a prior triptan to another triptan or ubrogepant.
Article in Pain management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Effectiveness of Rimegepant for the Acute Treatment of Migraine Among Participants Using Different Types of Preventive Therapy: Analyses from CONFIDENCE.Neurology and therapy · 2026Article
- Consistency of response to rimegepant for the acute treatment of migraine among real-world users - findings from the prospective observational CONFIDENCE study.The journal of headache and pain · 2026Observational
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveEvaluate the real-world experience of ubrogepant versus triptans for the acute treatment of migraine among participants switching from an oral triptan.
methodsUNIVERSE II was a prospective, longitudinal, survey-based, real-world study conducted in adult Migraine Buddy application users who self-reported a switch from an oral triptan to another oral triptan or ubrogepant. The 4-week study assessed treatment satisfaction, preference for the new treatment or previous triptan, and patient experience with new treatment against previous triptan.
resultsOf 694 participants, 211 were included after screening and accounting for dropouts (triptan,
conclusionThis real-world study demonstrated people with migraine who switched from a triptan to ubrogepant reported better outcomes than those who switched to a different triptan.
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Registered trials
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