ArticleThe Medico-legal journal2026
Extended absorption, implications: Rethinking alcohol pharmacokinetics in forensic calculations.
Article in The Medico-legal journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Forensic toxicologists routinely perform pharmacokinetic calculations for alcohol, such as retrograde extrapolation calculations that rely on assumptions about when alcohol absorption is complete. However, examination of current practice reveals a uniformity in applying standardised timing assumptions despite well-documented individual variation in alcohol pharmacokinetics. This paper highlights factors that can influence alcohol absorption and cause the absorption of alcohol to extend beyond the conventional 2-hour timeframe since the last drink. Various physiological conditions, including the presence of food, certain medications, medical conditions and other factors, can prolong alcohol absorption beyond 2 hours. Toxicologists performing pharmacokinetic calculations for alcohol should disclose that population averages regarding the absorption of alcohol may not apply to individual cases.
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