In one paragraphArticle in The Journal of infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
16 authors.
Magdalena PodkowikDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0009-0005-6772-3697 Alice TillmanDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Courtney TakatsDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0001-5116-7968 Heloise CarionLaboratory of Bacteriology, The Rockefeller University, New York, New York, USA.
Gregory PutzelDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Julian McWilliamsDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Guiqing WangDepartment of Pathology, NYU Grossman School of Medicine, New York, New York, USA.
Sigridh Munoz-GomezDepartment of Medicine, Division of Infectious Diseases, NYU Grossman Long Island School of Medicine, New York, New York, USA.ORCID 0000-0002-8836-2676 Karl DrlicaPublic Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ 07102, USA.
Alejandro PirontiAntimicrobial-Resistant Pathogens Program, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0002-7759-6776 Sarah HochmanDepartment of Medicine, Division of Infectious Diseases, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0003-2011-0453 Christopher KerantzasDepartment of Pathology, NYU Grossman School of Medicine, New York, New York, USA.ORCID 0000-0002-6745-9452 Bo ShopsinDepartment of Microbiology, New York University Grossman School of Medicine, New York, New York, USA.
Funding
IMMUNOHEMATOLOGY/TRANSFUSION MEDICINE RESEARCH TRAININGT32HL007974 · NHLBI · YALE UNIVERSITY · PI JEANNE E HENDRICKSON, Diane S Krause · 2001 to 2026
$8.1MHost-pathogen interactions during hospital adaptation of MRSAR01AI137336 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO, YANAI, ITAI · 2019 to 2022
$3.3MRole of precipitous virulence in invasiveness of community-acquired methicillin-rR01AI103268 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO, TORRES, VICTOR J. · 2013 to 2017
$2.1MCDC HHS U01CK000590NHLBI NIH HHS T32 HL007974NIAID NIH HHS R01 AI103268NIAID NIH HHS R01 AI137336NIH HHS AI137336NIH HHS AI140754NYULH Antimicrobial-Resistant Pathogens Program
6 · The paper itselfAbstract
Rapid molecular assays guiding treatment of methicillin-resistant Staphylococcus aureus detect SCCmec (Xpert) or the SCCmec-orfX junction (BCID2). Sequence variation in this region can disrupt primer binding, yielding false-negative results. Investigation of a missed bloodstream infection linked escape to a CRISPR-Cas-associated SCCmec variant, leading to identification of 64 variants from 45 patients-2% of 2432 screened. Misdiagnosis was restricted to clonal complex 5, a hospital-associated lineage; 11 of 40 SCCmec/junctions evaded detection by BCID2 or Xpert. Variants had mecA instability and circulated in healthcare settings. Our findings reveal a unique escape mechanism and underscore a threat to diagnostic accuracy.
Indexed as
CRISPR-Cas SystemsGenetic VariationMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsBacterial ProteinsHumansMolecular Diagnostic TechniquesRapid Diagnostic TestsBacterial ProteinsCRISPR-CasMRSArapid diagnosticsSCCmec
Identifiers
PMID41254867
PMCPMC13017219
What OpenQuestion holds
Textmetadata
LicenceCC BY
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