Evidence map›Paper›PMID 41254790›Full record

ArticleJournal of cheminformatics2025

NPBS Atlas: a comprehensive data resource for exploring the biological sources of natural products.

Tingjun Xu, Jinfang Dai, Yingyong Li, Junhong Zhou, Yingli Zhao, Weiming Chen, Xiao-Song Xue

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cheminformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tingjun XuState Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, People's Republic of China. xutingjun@sioc.ac.cn.
Jinfang DaiState Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, People's Republic of China.
Yingyong LiState Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, People's Republic of China.
Junhong ZhouState Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, People's Republic of China.
Yingli ZhaoState Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, People's Republic of China.
Weiming ChenState Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, People's Republic of China.
Xiao-Song XueState Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, People's Republic of China. xuexs@sioc.ac.cn.

Funding

CAS Project for Young Scientists in Basic Research YSBR-095Informatization Plan of Chinese Academy of Sciences CAS-WX2021SF-0307National Natural Science Foundation of China 22122104Strategic Priority Research Program of the Chinese Academy of Sciences XDB0590000
6 · The paper itself

Abstract

Natural products continue to play a pioneering role in drug discovery due to their extraordinary chemical and biological diversity. However, their full therapeutic potential remains largely underutilized, hindered by the fragmented documentation of biological origins in existing data resources. Here, we present natural product and biological source atlas (NPBS Atlas), a data resource covers over 218,000 natural products fully annotated with comprehensive biological sources, bioactivities, and references. The database established through systematic text mining and expert manual curation, places special emphasis on curating source organism data through the information of scientific nomenclature, taxonomic classification, source parts, and the source of Traditional Chinese Medicines. NPBS Atlas represents significant advancement in natural product data resources through its unique content, specialized annotations, and featured data, thereby enabling unprecedented exploration of nature-derived chemical diversity through biological context. The web interface of NPBS Atlas is freely available at https://biochemai.cstspace.cn/npbs/ .

Indexed as

BioactivitiesBiological sourcesData resourcesDrug discoveryMarine-derived compoundsNatural productsTCMsText mining

Identifiers

PMID41254790
PMCPMC12625013

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.