Observational studyBMC medicine2025
Increased risk of thromboembolism in patients with anorexia nervosa: a Danish nationwide registry-based study.
Observational study in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Coagulation activation in anorexia nervosa: increased tissue factor and prothrombin fragment 1+2.Research and practice in thrombosis and haemostasis · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCase reports suggest an increased risk of both venous thromboembolism and arterial thromboembolism in patients with anorexia nervosa (AN), even in the absence of known risk factors. Population-based studies on thromboembolism in patients with AN are missing. This study aims to establish the association in a registry-based nation-wide data set from Denmark.
methodsThis nationwide, observational registry-based cohort study used mandatory health care registries to identify the risk of thromboembolism in a cohort of patients with AN and in population controls matched on date of birth, area of residence, and sex. Thromboembolic outcomes were validated using specific criteria. The two groups were compared using Fine-Gray regression models.
resultsIn total, 12,676 patients (mean age 18.3 and 93.5% female) were matched with 63,049 controls. Median follow-up time was 9.5 years. For venous thromboembolism, the cumulative risk during the full follow-up period was 0.88% (n = 112) in the AN group and 0.12% (n = 79) in the control group with a subhazard ratio of 7.1 [5.3-9.5]. For arterial thromboembolism, the cumulative risk during the full follow-up period was 0.54% (n = 68) in the AN group and 0.05% (n = 36) in the control group (subhazard ratio 9.5 [6.4-14.1]).
conclusionsPatients with AN have a substantially increased risk of both arterial and venous thromboembolism, compared to the background population.
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