Evidence map›Paper›PMID 41254419›Full record

ArticleJournal of molecular histology2025

Amelioration of cisplatin-induced myocardial injury by nanocurcumin through antioxidant, anti-inflammatory, and calcium regulatory mechanisms.

Qamraa H Alqahtani, Tahani A ALMatrafi, Raeesa Mohammed, Ayman M Mahmoud, Iman H Hasan

Abstract read
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In one paragraph

Article in Journal of molecular histology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qamraa H AlqahtaniDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11495, Riyadh, Saudi Arabia.
Tahani A ALMatrafiDepartment of Anatomy, College of Medicine, King Saud University, 11461, Riyadh, Saudi Arabia.
Raeesa MohammedDepartment of Histology, College of Medicine, King Saud University, 11461, Riyadh, Saudi Arabia.
Ayman M MahmoudDepartment of Life Sciences, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, M1 5GD, UK.
Iman H HasanDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11495, Riyadh, Saudi Arabia. ihasan@ksu.edu.sa.

Funding

King Saud University ORF-2025-573
6 · The paper itself

Abstract

Cisplatin (CIS) is a widely used chemotherapeutic agent associated with cardiotoxicity. Nanocurcumin (N-CUR), a nano-formulated antioxidant and anti-inflammatory agent, has shown enhanced therapeutic efficacy over native curcumin. This study investigated the cardioprotective effects of N-CUR against CIS-induced cardiotoxicity in rats, focusing on oxidative stress, inflammation, apoptosis, and calcium (Ca

Indexed as

Anti-Inflammatory AgentsAntioxidantsCalciumCisplatinCurcuminAnimalsApoptosisCardiotoxicityInflammationMaleMyocardiumNanoparticlesOxidative StressRatsRats, WistarS100 ProteinsAnti-Inflammatory AgentsAntioxidantsCalciumCisplatinCurcuminnanocurcuminS100A1 proteinS100 ProteinsSarcoplasmic Reticulum Calcium-Transporting ATPasesCalcium homeostasisCardioprotectionCisplatinCurcuminInflammationOxidative stress

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.