Evidence map›Paper›PMID 41254404›Full record

ArticleNature computational science2026

Aligning brains into a shared space improves their alignment with large language models.

Arnab Bhattacharjee, Zaid Zada, Haocheng Wang, Bobbi Aubrey, Werner Doyle, Patricia Dugan, Daniel Friedman, Orrin Devinsky, Adeen Flinker, Peter J Ramadge and 3 more

Abstract read
In one paragraph

Article in Nature computational science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Arnab BhattacharjeeDepartment of Electrical and Computer Engineering, Princeton University, Princeton, NJ, USA. arnab@princeton.edu.ORCID http://orcid.org/0000-0003-2798-2350
Zaid ZadaDepartment of Psychology and Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0002-3096-0059
Haocheng WangDepartment of Psychology and Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0009-0000-8500-6054
Bobbi AubreyDepartment of Psychology and Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Werner DoyleNew York University Grossman School of Medicine, New York, NY, USA.
Patricia DuganNew York University Grossman School of Medicine, New York, NY, USA.
Daniel FriedmanNew York University Grossman School of Medicine, New York, NY, USA.
Orrin DevinskyNew York University Grossman School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0003-0044-4632
Adeen FlinkerNew York University Grossman School of Medicine, New York, NY, USA.
Peter J RamadgeDepartment of Electrical and Computer Engineering, Princeton University, Princeton, NJ, USA.
Uri HassonDepartment of Psychology and Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Ariel Goldstein *Google Research, Mountain View, CA, USA.
Samuel A Nastase *Department of Psychology and Princeton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0001-7013-5275

Funding

Speaker-listener coupling: a novel neural approach for assessing communicationDP1HD091948 · NICHD · PRINCETON UNIVERSITY · PI HASSON, URI · 2016 to 2021
$5.6M
Spatiotemporal Organization of the Inferior Frontal Gyrus During Speech Production - Resubmission - 1R01NS109367 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FLINKER, ADEEN · 2019 to 2023
$2.8M
CRCNS: Building and testing computational models of the neural basis of natural communicationR01DC022534 · NIDCD · PRINCETON UNIVERSITY · PI Uri Hasson · 2024 to 2026
$1.2M
NICHD NIH HHS DP1 HD091948NIDCD NIH HHS R01 DC022534NINDS NIH HHS R01 NS109367
6 · The paper itself

Abstract

Recent research demonstrates that large language models can predict neural activity recorded via electrocorticography during natural language processing. To predict word-by-word neural activity, most prior work evaluates encoding models within individual electrodes and participants, limiting generalizability. Here we analyze electrocorticography data from eight participants listening to the same 30-min podcast. Using a shared response model, we estimate a common information space across participants. This shared space substantially enhances large language model-based encoding performance and enables denoising of individual brain responses by projecting back into participant-specific electrode spaces-yielding a 37% average improvement in encoding accuracy (from r = 0.188 to r = 0.257). The greatest gains occur in brain areas specialized for language comprehension, particularly the superior temporal gyrus and inferior frontal gyrus. Our findings highlight that estimating a shared space allows us to construct encoding models that better generalize across individuals.

Identifiers

PMID41254404
PMCPMC13456310

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.