Evidence map›Paper›PMID 41254400›Full record

ArticleLasers in medical science2025

In vitro study of high-power Er: YAG laser parameters for the management of dentin hypersensitivity in hypomineralized permanent teeth.

Giovanna Bueno Marinho, Patrícia Moreira de Freitas, Luciane Hiramatsu Azevedo, Daniela Fátima Teixeira Silva, Denise Maria Zezell, Bruna Cordeiro Amarante, Victor Elias Arana-Chavez, Marcelo Bönecker

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giovanna Bueno MarinhoDepartment of Paediatric Dentistry and Orthodontics, University of São Paulo School of Dentistry, São Paulo, SP, Brazil. giovannamarinho@usp.br.
Patrícia Moreira de FreitasSpecial Laboratory of Lasers in Dentistry, Department of Restorative Dentistry, University of São Paulo School of Dentistry, São Paulo, SP, Brazil. pfreitas@usp.br.
Luciane Hiramatsu AzevedoSpecial Laboratory of Lasers in Dentistry, Department of Restorative Dentistry, University of São Paulo School of Dentistry, São Paulo, SP, Brazil.
Daniela Fátima Teixeira SilvaCenter for Lasers and Applications, Nuclear and Energy Research Institute (CNEN/IPEN-SP), São Paulo, Brazil.
Denise Maria ZezellCenter for Lasers and Applications, Nuclear and Energy Research Institute (CNEN/IPEN-SP), São Paulo, Brazil.
Bruna Cordeiro AmaranteDepartment of Paediatric Dentistry and Orthodontics, University of São Paulo School of Dentistry, São Paulo, SP, Brazil.
Victor Elias Arana-ChavezDepartment of Biomaterials and Oral Biology, University of São Paulo School of Dentistry, São Paulo, SP, Brazil.
Marcelo BöneckerDepartment of Paediatric Dentistry and Orthodontics, University of São Paulo School of Dentistry, São Paulo, SP, Brazil. bonecker@usp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dentin hypersensitivity (DH) is characterized by intense, short-lasting pain, triggered by dentin exposure to different stimuli. It is often associated with hypomineralized teeth due to increased enamel porosity and exposed dentinal tubules. The high-power Er: YAG laser has emerged as a promising therapeutic strategy for the treatment of this condition. The aim of this in vitro study was to test different protocols for managing dentin hypersensitivity in hypomineralized teeth using a high-power Er: YAG laser. Six protocols were evaluated, varying in power, frequency, application mode, and the use of cooling. Qualitative analysis of morphological changes were evaluated by scanning electron microscopy (SEM). Further, the most promising protocol - 20 mJ, 10 Hz, 0.20 watts, applied in focused mode, without cooling - was selected for assessing intrapulpal temperature variation using thermocouples connected to a monitoring system. The SEM images showed that this protocol promoted homogeneous surface melting of dentin, effectively sealing the dentinal tubules without inducing a thermal increase greater than 2 °C. These findings support the feasibility of using the Er: YAG laser with conservative parameters and no cooling as a safe and effective alternative for the management of DH in hypomineralized teeth. However, clinical trials are recommended to validate its applicability in pediatric dentistry.

Indexed as

Dentin SensitivityLasers, Solid-StateDentinDentition, PermanentHumansIn Vitro TechniquesMicroscopy, Electron, ScanningDentin hypersensitivityEr:YAG laserHypomineralizationIntrapulpal temperatureScanning electron microscopy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.