ReviewJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2025
Atrial fibrillation in continuous flow-left ventricular assist device (CF-LVAD) patients: impact on pathophysiology.
Review in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Indication for durable mechanical circulatory support: an expert opinion review.ESC heart failure · 2026Review
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Continuous Flow -Left Ventricular Assist Devices (CF-LVADs) remain the mainstay in end stage HFrEF patients with refractory Stage D HF. AF is common in patients supported on CF-LVADs, with a significantly increasing number developing new-onset AF post LVAD implantation. This review will summarize the effects of atrial fibrillation on LVAD physiology and its impact on outcomes. Literature search for this qualitative review was done using Google Scholar and PubMed. Only studies in adult human LVAD patients were included. The keywords used were atrial fibrillation in LVADs, effect of atrial fibrillation on functional mitral regurgitation /tricuspid regurgitation, effect on right ventricular failure, pump thrombosis and stroke and gender differences in outcomes.The main aspects addressed are effect on LVAD hemodynamics, the complexinteractions between low pulse pressure and atrial fibrillation leading to pump thrombosis and stroke , the role of atrial fibrillation in the initiation and progression ofright ventricular failure, impact on valvular regurgitation (Functional Mitral /TricuspidRegurgitation), utility of Cardiac Resynchronization Therapy post LVAD implant anduse of AI-driven technologies in risk factor identification to help identify novel risk factors important in predicting prognosis to improve outcomes. Use of AI technologies to identify novel risk factors for atrial fibrillation post LVADsurgery is warranted in the context of race, ethnicity and gender. Further studies areneeded to address optimal pacing strategies in LVAD patients with cardiac resynchronization therapy to institute guidelines for use of this therapy post LVAD implantation especially in the context of co-existing atrial fibrillation.
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