ArticleCardiovascular and interventional radiology2026
CT-Guided Dual-Fluorescent Marking to Localize Small Pulmonary Nodules for Robotic Sublobar Resection: Technical Note from 84 Consecutive Cases.
Article in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Comparison of Single Fiber Transperineal Laser Ablation and Radiofrequency Ablation in the Treatment of Benign Prostatic Hyperplasia.Cardiovascular and interventional radiology · 2026Article
- Preoperative and intraoperative localization of small pulmonary nodules for thoracoscopic surgery: a contemporary narrative review.Journal of robotic surgery · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo describe a CT-guided dual-fluorescent marking technique (methylene blue + indocyanine green stabilized in fibrin-thrombin matrix) for intraoperative localization of non-palpable pulmonary nodules during robotic-assisted thoracic surgery (RATS) and to report feasibility and key outcomes. MATERIALS AND
methodsRetrospective, single-center series of 84 consecutive patients with solid or subsolid nodules ≤ 2 cm referred for RATS (Oct/2021-Oct/2024). Under general anesthesia, a 22-G Chiba needle was used for CT-guided percutaneous injection of a standardized solution (1 mL 1% methylene blue + 1 mL indocyanine green + 3 mL fibrin-thrombin + 1 mL iodinated contrast; typical injected volume 0.2-1.0 mL). Resection proceeded using near-infrared Firefly® imaging. OUTCOMES: intraoperative identification, complete resection, margin status, timing, and complications. Prespecified subgroup analysis compared subsolid vs. solid lesions.
resultsAll 84 nodules were localized intraoperatively and resected with negative margins; no conversion to open surgery occurred and no complications attributable to marking were recorded. Mean operative time was 163.7 ± 66.7 min; mean interval between marking and surgery was 74.6 ± 20.6 min. Patients with subsolid nodules were older (70.5 vs. 63.1 years, p = 0.003) and had larger lesions (14.7 vs. 11.4 mm, p = 0.010). During a mean clinical follow-up of 17.3 months, no local recurrences were observed.
conclusionCT-guided dual-fluorescent marking is a practical, fluoroscopy-free localization strategy that integrates smoothly with RATS workflows and enables reliable sublobar resections with negative margins in this series. The incremental contribution of methylene blue beyond ICG could not be isolated and warrants prospective evaluation. However, this study did not include a control group, such as conventional marking techniques, which should be considered when interpreting the results.
Indexed as
Identifiers
41254236What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.