ArticleScientific reports2025
Modeling dysentery spread and the impact of public awareness on control dynamics.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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Corrections and comments
- Erratum issued
Authors and funding
10 authors.
Funding
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Abstract
Dysentery remains a leading cause of morbidity and mortality in developing regions, exacerbated by poor sanitation and limited access to healthcare. This study develops a novel mathematical model to analyze the transmission dynamics of dysentery and evaluate the effectiveness of control strategies, with a specific focus on the impact of public awareness. The model uniquely stratifies the population into compartments based on health education status and disease severity, allowing for a nuanced analysis of intervention impacts. We derived a key epidemiological threshold, the basic reproduction number, to determine the conditions for disease elimination or persistence. Our analysis demonstrates that a disease-free equilibrium is locally and globally stable when this threshold is below one. Furthermore, we employed optimal control theory to simulate and compare three intervention strategies: public awareness campaigns, hygiene and sanitation improvements, and treatment of infected individuals. Numerical simulations reveal that while each intervention alone reduces disease burden, a combined strategy is the most effective and cost-efficient approach to curtailing outbreaks. These findings underscore the critical importance of integrated public health policies that synergize education, prevention, and treatment for effective and sustainable dysentery control.
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