Evidence map›Paper›PMID 41253724›Full record

ArticleEnvironmental science & technology2025

Demographic-Driven Wastewater-Based Epidemiology: Refining Population Estimates for Enhanced Chemical Monitoring.

Kishore Kumar Jagadeesan, Megan Robertson, John Bagnall, Barbara Kasprzyk-Hordern

Abstract read
In one paragraph

Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kishore Kumar JagadeesanDepartment of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, U.K.ORCID 0000-0003-0916-256X
Megan RobertsonCentre of Excellence in Water-Based Early Warning Systems for Health Protection, Bath BA2 7AY, U.K.
John BagnallCentre of Excellence in Water-Based Early Warning Systems for Health Protection, Bath BA2 7AY, U.K.
Barbara Kasprzyk-HordernDepartment of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY, U.K.ORCID 0000-0002-6809-2875

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wastewater-based epidemiology (WBE) is a vital tool for public health and environmental monitoring, yet accurate population estimation and demographic profiles within wastewater treatment plant (WWTP) catchments remain a challenge. This study integrates high-resolution 2021 UK Census data, NHS patient registration records, and WWTP chemical parameters to refine population estimates and assess demographic influences on wastewater composition. We compared four statistical models: Simple Approach (SA), Density-Adjusted Bootstrapping (BtD), Density-Adjusted Bootstrapping with Overlap (BtDO), and Bayesian Hierarchical Modeling (ByD), across four diverse UK catchments (12,000-960,000). The BtDO method provided the most consistent estimates, with relative uncertainties as low as 1.5% in larger catchments. Demographic analysis revealed that older populations and higher deprivations correlated with elevated pharmaceutical load (e.g., analgesics,

Indexed as

Environmental MonitoringWastewaterBayes TheoremDemographyHumansWater Pollutants, ChemicalWastewaterWater Pollutants, ChemicalBayesian modelingchemical biomarkersenvironmental riskNHS registrationpopulation estimationwastewater-based epidemiology

Identifiers

PMID41253724
PMCPMC12676738

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.