Evidence map›Paper›PMID 41253711›Full record

ArticleJournal of applied clinical medical physics2025

Reference dosimetry data and machine performance comparison for tomotherapy delivery systems audited by IROC.

Paige A Taylor, Hunter Mehrens, Mallory C Glenn, Fre'Etta Brooks, Hayden Scott, Lian Duan, Taylor Meyers, Diana Carrasco Rojas, Michael Yang, Paola Alvarez and 3 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Paige A TaylorDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.ORCID https://orcid.org/0000-0001-9720-8059
Hunter MehrensDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.
Mallory C GlennDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.
Fre'Etta BrooksDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.
Hayden ScottDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.ORCID https://orcid.org/0000-0003-1066-1999
Lian DuanDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.ORCID https://orcid.org/0000-0001-9783-3399
Taylor MeyersDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.
Diana Carrasco RojasDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.
Michael YangDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.
Paola AlvarezDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.ORCID https://orcid.org/0000-0002-3788-3391
Jessica LowensteinDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.
Andrea MolineuDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.
Stephen F KryDepartment of Radiation Physics, The University of MD Anderson Cancer Center, Houston, Texas, USA.

Funding

National Institute of Health CA180803
6 · The paper itself

Abstract

The aim of this work was to compare the imaging and radiation oncology core (IROC) on-site TomoTherapy dosimetry measurement results among institutions and generate a dataset of basic dosimetric properties for TomoTherapy units. Independent ion chamber measurements for nine TomoTherapy units were acquired by IROC physicists between 2008 and 2023. Measurements included percent depth dose (PDD) in a water tank and off axis factors (OAF) in a solid Polystyrene phantom. The independent measurements collected during the on-site audits for each TomoTherapy system were compared to corresponding TomoTherapy TPS calculations from the institution to assess agreement. Numeric measurement values and comparative ratios are compiled and tabulated according to measurement type (i.e., PDD and OAF). The distribution of the measurements was evaluated, and the mean, standard deviation of the mean, and median values are reported. These data provide an independent guide describing the inherent performance characteristics of TomoTherapy units. Such data may serve as a secondary check for users wishing to verify their beam model commissioning and ongoing quality assurance efforts.

Indexed as

NeoplasmsPhantoms, ImagingQuality Assurance, Health CareRadiometryRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedHumansRadiotherapy Dosageauditquality assuranceTomoTherapy

Identifiers

PMID41253711
PMCPMC12626754

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.