Evidence map›Paper›PMID 41253503›Full record

ArticleRenal failure2025

Comparable renal effects of histidine-tryptophan-ketoglutarate and DelNido cardioplegia in a porcine model of cardiac arrest.

Maja-Theresa Dieterlen, Jagdip Kang, Paul Schütte, Kristin Klaeske, Susann Oßmann, Philipp Kiefer, Marcel Vollroth, Michael A Borger, Alexandro Hoyer

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maja-Theresa DieterlenUniversity Clinic of Cardiac Surgery, University of Leipzig, Heart Center Leipzig, HELIOS Clinic, Leipzig, Germany.
Jagdip KangUniversity Clinic of Cardiac Surgery, University of Leipzig, Heart Center Leipzig, HELIOS Clinic, Leipzig, Germany.
Paul SchütteUniversity Clinic of Cardiac Surgery, University of Leipzig, Heart Center Leipzig, HELIOS Clinic, Leipzig, Germany.
Kristin KlaeskeUniversity Clinic of Cardiac Surgery, University of Leipzig, Heart Center Leipzig, HELIOS Clinic, Leipzig, Germany.
Susann OßmannUniversity Clinic of Cardiac Surgery, University of Leipzig, Heart Center Leipzig, HELIOS Clinic, Leipzig, Germany.
Philipp KieferUniversity Clinic of Cardiac Surgery, University of Leipzig, Heart Center Leipzig, HELIOS Clinic, Leipzig, Germany.
Marcel VollrothUniversity Clinic of Cardiac Surgery, University of Leipzig, Heart Center Leipzig, HELIOS Clinic, Leipzig, Germany.
Michael A BorgerUniversity Clinic of Cardiac Surgery, University of Leipzig, Heart Center Leipzig, HELIOS Clinic, Leipzig, Germany.
Alexandro HoyerUniversity Clinic of Cardiac Surgery, University of Leipzig, Heart Center Leipzig, HELIOS Clinic, Leipzig, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) is a serious complication following on-pump cardiac surgery. Choosing the cardioplegic solution with the most appropriate myocardial protection and lowest grade of AKI could improve patient outcome. We compared the crystalloid histidine-tryptophan-ketoglutarate (HTK) solution and a Jonosteril

Indexed as

Acute Kidney InjuryCardioplegic SolutionsHeart ArrestHeart Arrest, InducedAnimalsCardiopulmonary BypassDisease Models, AnimalElectrolytesGlucoseKidneyLidocaineMagnesium SulfateMannitolOxidative StressPotassium ChlorideProcaineBretschneider cardioplegic solutionCardioplegic SolutionsDel Nido cardioplegia solutionElectrolytesGlucoseLidocaineMagnesium SulfateMannitolPotassium ChlorideProcaineSodium BicarbonateSolutionsAcute kidney injuryanimal modelcardioplegiadel nido solutionhistidine-tryptophan-ketoglutarate solutionsingle shot cardioplegia

Identifiers

PMID41253503
PMCPMC12628664

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.