ArticleAsian spine journal2026
Effect of mechanical bowel preparation with antibiotics and probiotics on postoperative ileus in patients undergoing posterior lumbar spine surgeries: a randomized controlled trial.
Article in Asian spine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Letter to the editor: Effect of mechanical bowel preparation with antibiotics and probiotics on postoperative ileus in patients undergoing posterior lumbar spine surgeries.Asian spine journal · 2026Article
- Response to the letter to the editor: Effect of mechanical bowel preparation with antibiotics and probiotics on postoperative ileus in patients undergoing posterior lumbar spine surgeries: a randomized controlled trial.Asian spine journal · 2026Article
- Early Discontinuation of Prophylactic Antibiotics Is Not Associated with Increased Surgical Site Infection Risk in Spine Surgery: A Nationwide Cohort Study.Antibiotics (Basel, Switzerland) · 2026Article
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8 authors.
Funding
Abstract
STUDY
designRandomized controlled trial (RCT). PURPOSE: This study aimed to determine the impact of mechanical bowel preparation (MBP) before surgery on postoperative ileus (POI) after elective lumbar spine procedures conducted via a posterior approach. OVERVIEW OF LITERATURE: Postoperative Ileus occurs in 5%-12% of spine surgeries. The data relating to spine surgeries is sparse. Previous studies have not shown a significant effect of MBP. However, most of these studies have been conducted on patients undergoing spine surgeries through anterior approaches.
methodsThis RCT included 60 patients (30 in control and 30 in intervention) between 18 and 80 years old, scheduled for elective single or double-level lumbar spine surgeries through the posterior approach. Intervention group (MBP) received PEGLEC, tablet Metronidazole 400 mg twice daily (BD), tablet Cefuroxime 500 mg BD, and probiotic (Bacillus clausii ) on pre-operation day, whereas the control (non-MBP) had no specific bowel preparation but received only a placebo. Outcome parameters included time to first flatus, bowel sound, and first defecation, which were compared between the two groups.
resultsDemographic data such as age, sex, body mass index, level of surgery, and intraoperative data such as duration of surgery and blood loss were similar without significant differences. The time to first flatus, bowel sounds, and first defecation was not statistically significant, but POI was seen in 6.67% of patients, all belonging to the MBP group. No correlation observed between the duration of the ileus and the intraoperative blood loss and duration of surgery.
conclusionsBowel preparation may not be necessary for patients undergoing posterior lumbar spine surgery involving a maximum of two levels.
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