Evidence map›Paper›PMID 41253072›Full record

ArticleSurgery2026

Implementation of an electronic health record-based tool increases administration of venous thromboembolism chemoprophylaxis in trauma.

Zongyang Mou, Parisa Oviedo, Louis Perkins, Todd W Costantini, Jeanne G Lee, Allison E Berndtson, Laura N Haines, Aaron Marshall, Jarrett E Santorelli

Abstract read
In one paragraph

Article in Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zongyang MouDepartment of Surgery, Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, UC San Diego Health, San Diego, CA.
Parisa OviedoDepartment of Surgery, Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, UC San Diego Health, San Diego, CA. Electronic address: poviedo@health.ucsd.edu.
Louis PerkinsDepartment of Surgery, Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, UC San Diego Health, San Diego, CA.
Todd W CostantiniDepartment of Surgery, Division of Trauma, Division of Critical Care and Acute Care Surgery, University of Minnesota, Minneapolis, MN.
Jeanne G LeeDepartment of Surgery, Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, UC San Diego Health, San Diego, CA.
Allison E BerndtsonDepartment of Surgery, Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, UC San Diego Health, San Diego, CA.
Laura N HainesDepartment of Surgery, Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, UC San Diego Health, San Diego, CA.
Aaron MarshallDepartment of Surgery, Division of Trauma and Acute Care Surgery, University of Colorado Hospital, Aurora, CO.
Jarrett E SantorelliDepartment of Surgery, Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, UC San Diego Health, San Diego, CA.

Funding

San Diego Biomedical Informatics Education & Research (SABER)T15LM011271 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHAMIM NEMATI · 2012 to 2026
$9.7M
NLM NIH HHS T15 LM011271
6 · The paper itself

Abstract

introductionTimely initiation of venous thromboembolism chemoprophylaxis remains a challenge in trauma and is recognized as a quality benchmark for the American College of Surgeons Trauma Quality Improvement Program. There are several workflow-related barriers that limit timely administration of venous thromboembolism chemoprophylaxis. Tools embedded within the electronic health record can aid protocol compliance as they are integrated in the care workflow. We hypothesized that implementing an electronic health record-based clinical decision support tool improves venous thromboembolism chemoprophylaxis administration in patients with trauma admission.

methodsWe conducted a pre- and postintervention study in patients admitted to a level 1 trauma center with a hospital length of stay greater than 2 days from November 2018 to May 2021. An electronic health record tool updated in real time indicating venous thromboembolism chemoprophylaxis status was incorporated into the daily handoff list in February 2020. No other initiatives were implemented at this time. Outcomes were the change in percentage of patients receiving at least 1 venous thromboembolism chemoprophylaxis dose during hospitalization and time to first chemoprophylaxis dose.

resultsThere were 4,311 patients: 2,174 in the preintervention group and 2,137 in the postintervention group. The percentage of patients receiving venous thromboembolism chemoprophylaxis increased from 57.9% before intervention to 81.8% after intervention (P < .001). Concurrently, there was a decrease in average time to initiation of pharmacologic venous thromboembolism chemoprophylaxis from 2.2 days to 1.6 days (P < .001).

conclusionWe found that implementing an electronic health record-embedded tool increased the proportion of patients receiving venous thromboembolism chemoprophylaxis and decreased the time to first dose of venous thromboembolism chemoprophylaxis. This demonstrates the benefits of using electronic health record-based tools to support trauma protocol compliance.

Indexed as

AnticoagulantsChemopreventionDecision Support Systems, ClinicalElectronic Health RecordsVenous ThromboembolismWounds and InjuriesAdultAgedFemaleHumansLength of StayMaleMiddle AgedQuality ImprovementTrauma CentersAnticoagulants

Identifiers

PMID41253072
PMCPMC13435931

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.