Evidence map›Paper›PMID 41252453›Full record

ArticlePLoS neglected tropical diseases2025

Phenotypic variation in populations of the mosquito vector, Aedes aegypti, and implications for predicting the effects of temperature and climate change on dengue transmission.

Nina L Dennington, Marissa K Grossman, Janet L Teeple, Leah R Johnson, Marta S Shocket, Elizabeth A McGraw, Matthew B Thomas

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nina L DenningtonDepartment of Entomology, The Pennsylvania State University, University Park, Pennsylvania, United States of America.ORCID 0000-0003-3266-156X
Marissa K GrossmanDepartment of Entomology, The Pennsylvania State University, University Park, Pennsylvania, United States of America.
Janet L TeepleDepartment of Entomology, The Pennsylvania State University, University Park, Pennsylvania, United States of America.
Leah R JohnsonDepartment of Statistics, Virginia Tech, Blacksburg, Virginia, United States of America.
Marta S ShocketDepartment of Geography, University of Florida, Gainesville, Florida, United States of America.
Elizabeth A McGrawThe Center for Infectious Disease Dynamics, The Huck Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, United States of America.
Matthew B ThomasDepartment of Entomology & Nematology, University of Florida, Gainesville, Florida, United States of America.

Funding

National Science Foundation DEB-1518681
6 · The paper itself

Abstract

There is concern that increases in temperature due to climate change could lead to shifts in the transmission dynamics and distribution of mosquito vectors. Many current models assume there are 'average' thermal performance curves for a given vector species' life-history traits. However, this 'one-size-fits-all' assumption ignores the potential for standing phenotypic variation in life-history traits to create population-specific differences in thermal performance. In this study, we explored thermal performance of five independent field populations of Ae. aegypti from Mexico, together with a standard laboratory strain. We reared these six populations at temperatures between 13°C- 37°C to generate thermal performance curves for a suite of life-history traits. Composite models integrating these traits revealed the effects of temperature on population growth rates and dengue virus transmission potential. The results provide strong evidence for the potential for local adaptation in Ae. aegypti populations, challenging the applicability of 'one-size-fits-all' thermal performance models to assess climate impact on mosquito-borne diseases.

Indexed as

AedesClimate ChangeDengueMosquito VectorsAnimalsDengue VirusFemaleHumansMexicoPhenotypeTemperature

Identifiers

PMID41252453
PMCPMC12643283

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.