Evidence map›Paper›PMID 41252304›Full record

SynthesisJournal of neuromuscular diseases2026

Unveiling MYH2-related myopathy: Histological-genetic insights from a case series and systematic review.

Beatrice Labella, Guy Brochier, Maud Beuvin, Emmanuelle Lacene, Anais Chanut, Angeline Madelaine, Clemence Labasse, Aurelie Méneret, Andreas Roos, Heike Kölbel and 24 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of neuromuscular diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Beatrice LabellaNeuromuscular Morphology Unit, Myology Institute, Groupe Hospitalier Universitaire Pitié-Salpêtrière, Paris, France.
Guy BrochierNeuromuscular Morphology Unit, Myology Institute, Groupe Hospitalier Universitaire Pitié-Salpêtrière, Paris, France.
Maud BeuvinNeuromuscular Morphology Unit, Myology Institute, Groupe Hospitalier Universitaire Pitié-Salpêtrière, Paris, France.
Emmanuelle LaceneNeuromuscular Morphology Unit, Myology Institute, Groupe Hospitalier Universitaire Pitié-Salpêtrière, Paris, France.
Anais ChanutNeuromuscular Morphology Unit, Myology Institute, Groupe Hospitalier Universitaire Pitié-Salpêtrière, Paris, France.
Angeline MadelaineNeuromuscular Morphology Unit, Myology Institute, Groupe Hospitalier Universitaire Pitié-Salpêtrière, Paris, France.
Clemence LabasseNeuromuscular Morphology Unit, Myology Institute, Groupe Hospitalier Universitaire Pitié-Salpêtrière, Paris, France.
Aurelie MéneretNeurology Unit, Groupe Hospitalier Universitaire La Pitié-Salpêtrière, Paris, France.
Andreas RoosDepartment of Pediatric Neurology, Centre for Neuromuscular Disorders, Centre for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
Heike KölbelDepartment of Pediatric Neurology, Centre for Neuromuscular Disorders, Centre for Translational Neuro- and Behavioral Sciences, University Hospital Essen, Essen, Germany.
Adrian LevineDivision of Pathology, Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
Grace YoonDivision of Clinical and Metabolic Genetics, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Juliette SvahnPathophysiology and Genetics of Neuron and Muscle, CNRS UMR 5261, INSERM U1315, University of Lyon 1, Faculté de Médecine Lyon Est, Lyon, France.
Francoise BouhourENMG and Neuromuscular disorders, Center of Neuromuscular disorders PACA-Réunion-Rhône-Alpes, Pierre-Wertheimer Hospital, Hospital of Lyon, Bron, France.
Natalie StreichenbergerFaculté de Médecine Rockefeller, Institut NeuroMyoGène-PGNM, Université Claude Bernard Lyon, Lyon, France.
Aleksandra Nadaj-PaklezaCentre de Reference des Maladies Neuromusculaires Nord-Est-Ile de France, Department of Neurology, University Hospital Centre, Strasbourg, France.
Edoardo MalfattiReference Center for Neuromuscular Disorders, Henri Mondor University Hospital, APHP, Créteil, France.
Guillaume BassezCentre de Reference des Maladies Neuromusculaires, Groupe Hospitalier Universitaire Pitié-Salpêtrière, APHP, Paris, France.
Anthony BehinCentre de Reference des Maladies Neuromusculaires, Groupe Hospitalier Universitaire Pitié-Salpêtrière, APHP, Paris, France.
Pascal LaforetNeurology Department, Raymond Poincaré University Hospital, APHP, Garches, France.
Rocio Nur Villar-QuilesCentre de Reference des Maladies Neuromusculaires, Groupe Hospitalier Universitaire Pitié-Salpêtrière, APHP, Paris, France.
Sarah Leonard-LouisNeuropathology Unit, Department of Neuropathology, Groupe Hospitalier Universitaire La Pitié-Salpêtrière, Paris, France.
Thierry MaisonobeDepartment of Clinical Neurophysiology, Pitié-Salpêtrière University Hospital, Paris, France.
Tanya StojkovicCentre de Reference des Maladies Neuromusculaires, Groupe Hospitalier Universitaire Pitié-Salpêtrière, APHP, Paris, France.
Bruno EymardCentre de Reference des Maladies Neuromusculaires, Groupe Hospitalier Universitaire Pitié-Salpêtrière, APHP, Paris, France.
Norma Beatriz RomeroNeuromuscular Morphology Unit, Myology Institute, Groupe Hospitalier Universitaire Pitié-Salpêtrière, Paris, France.
Alessandro PadovaniDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Massimiliano FilostoDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Denise CassandriniImmunology Unit, University Hospital, Azienda Ospedaliera Universitaria Integrata, Verona, Verona, Italy.
Valerie BiancalanaLaboratoire de Diagnostic Génétique, Faculté de Médecine, CHRU, Strasbourg, France.
John RenduUniversity Grenoble Alpes, INSERM U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, Grenoble, France.
Kiran PolavarapuChildren's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, ON, Canada.
Corinne MétaySorbonne University, Myology research center, UMRS 974, Paris, France.
Teresinha EvangelistaNeuromuscular Morphology Unit, Myology Institute, Groupe Hospitalier Universitaire Pitié-Salpêtrière, Paris, France.ORCID 0000-0002-1329-9131

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenic variants in the

Indexed as

Muscular DiseasesMyosin Heavy ChainsAdolescentAdultChildFemaleHumansMaleMiddle AgedMuscle, SkeletalMutationYoung AdultMyosin Heavy Chainselectron microscopygenetic variantsmuscle pathologymyosin heavy chain 2myosinopathyophthalmoparesis

Identifiers

PMID41252304
PMCPMC13442676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.