Evidence map›Paper›PMID 41252252›Full record

ArticleChemistryOpen2026

Exploration of the Phytochemical and Antidiabetic Properties of Teucrium polium: A Natural Asset for Type 2 Diabetes Management.

Hajar El Ouadni, Aziz Drioiche, Fadoua El Makhoukhi, Omkulthom Al Kamaly, Hannou Zerkani, Smail Amalich, Imane Tagnaout, Mohamed Radi, Yahya Cherrah, Touriya Zair and 1 more

Abstract read
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In one paragraph

Article in ChemistryOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hajar El OuadniResearch Team on the Toxicity and Pharmacodynamics of Aromatic and Medicinal Plants (ERTP.PAM), Pharmacology and Toxicology Laboratory, Rabat Faculty of Medicine and Pharmacy (FMPR), Mohammed V University (UMV), Rabat, B.P., 6203, Morocco.
Aziz DrioicheResearch Team of Chemistry of Bioactive Molecules and the Environment, Laboratory of Innovative Materials and Biotechnology of Natural Resources, Faculty of Sciences, Moulay Ismaïl University, B.P., 11201, Zitoune, Meknes, 50070, Morocco.ORCID 0000-0001-9036-5289
Fadoua El MakhoukhiResearch Team of Chemistry of Bioactive Molecules and the Environment, Laboratory of Innovative Materials and Biotechnology of Natural Resources, Faculty of Sciences, Moulay Ismaïl University, B.P., 11201, Zitoune, Meknes, 50070, Morocco.
Omkulthom Al KamalyDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O., Box, 84428, Riyadh, 11671, Saudi Arabia.
Hannou ZerkaniResearch Team of Chemistry of Bioactive Molecules and the Environment, Laboratory of Innovative Materials and Biotechnology of Natural Resources, Faculty of Sciences, Moulay Ismaïl University, B.P., 11201, Zitoune, Meknes, 50070, Morocco.
Smail AmalichLaboratory of Phytochemistry, National Agency of Medicinal and Aromatic Plants (ANPMA), BP:, 159, Taounate Principale, Taounate, 34000, Morocco.
Imane TagnaoutResearch Team of Chemistry of Bioactive Molecules and the Environment, Laboratory of Innovative Materials and Biotechnology of Natural Resources, Faculty of Sciences, Moulay Ismaïl University, B.P., 11201, Zitoune, Meknes, 50070, Morocco.
Mohamed RadiResearch Team of Chemistry of Bioactive Molecules and the Environment, Laboratory of Innovative Materials and Biotechnology of Natural Resources, Faculty of Sciences, Moulay Ismaïl University, B.P., 11201, Zitoune, Meknes, 50070, Morocco.
Yahya CherrahResearch Team on the Toxicity and Pharmacodynamics of Aromatic and Medicinal Plants (ERTP.PAM), Pharmacology and Toxicology Laboratory, Rabat Faculty of Medicine and Pharmacy (FMPR), Mohammed V University (UMV), Rabat, B.P., 6203, Morocco.
Touriya ZairResearch Team of Chemistry of Bioactive Molecules and the Environment, Laboratory of Innovative Materials and Biotechnology of Natural Resources, Faculty of Sciences, Moulay Ismaïl University, B.P., 11201, Zitoune, Meknes, 50070, Morocco.
Katim AlaouiResearch Team on the Toxicity and Pharmacodynamics of Aromatic and Medicinal Plants (ERTP.PAM), Pharmacology and Toxicology Laboratory, Rabat Faculty of Medicine and Pharmacy (FMPR), Mohammed V University (UMV), Rabat, B.P., 6203, Morocco.

Funding

Princess Nourah bint Abdulrahman UniversityPrincess Nourah bint Abdulrahman University Researchers PNURSP2025R917
6 · The paper itself

Abstract

Type 2 diabetes (T2D) is characterized by hyperglycemia due to impaired insulin utilization, and current therapies face notable limitations. This study investigated the chemical composition and biological activities of Teucrium polium essential oils and extracts, with a focus on their antidiabetic, antimicrobial, and antioxidant properties. Essential oil from aerial parts (yield 1.65%) was obtained by hydrodistillation; extracts were prepared by aqueous decoction (E0) and Soxhlet (aqueous, E1; hydroethanolic, E2). HPLC-UV-Vis-ESI-MS and GC-MS identified bioactives. The oil was dominated by carvacrol (28.10%), thymol (26.28%), γ-terpinene (12.11%), and o-cymene (15.59%). E0 was rich in poliumoside (36.45%); E1 contained verbascoside (9.42%) and isorhamnetin-3-O-rutinoside (9.68%); E2 was dominated by apigenin-7-rutinoside (21.18%). Antioxidant assays showed 85% DPPH inhibition at 100 µgmL

Indexed as

Diabetes Mellitus, Type 2Hypoglycemic AgentsOils, VolatilePhytochemicalsPlant ExtractsTeucriumAnimalsAnti-Infective AgentsAntioxidantsMicrobial Sensitivity TestsAnti-Infective AgentsAntioxidantsHypoglycemic AgentsOils, VolatilePhytochemicalsPlant Extractsantidiabeticantimicrobialantioxidantapigenin‐7‐rutinosidecarvacrolpoliumosideteucrium poliumverbascoside

Identifiers

PMID41252252
PMCPMC13054243

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.