Evidence map›Paper›PMID 41252167›Full record

ArticleJAMA network open2025

Long-Term Recurrence and the Safety of Mesh Use After Emergency Ventral Hernia Repair.

Erin E Isenberg, Brian T Fry, Joshua Sinamo, Ryan A Howard, Anne P Ehlers, Jenny M Shao, Raymond A Jean, Dana A Telem

Abstract read
In one paragraph

Article in JAMA network open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Erin E IsenbergDepartment of Surgery, The University of Texas at Southwestern Medical Center, Dallas.
Brian T FryDepartment of Surgery, University of Michigan Medical School, Ann Arbor.
Joshua SinamoDepartment of Surgery, University of Michigan Medical School, Ann Arbor.
Ryan A HowardDepartment of Surgery, University of Michigan Medical School, Ann Arbor.
Anne P EhlersDepartment of Surgery, University of Michigan Medical School, Ann Arbor.
Jenny M ShaoDepartment of Surgery, University of Michigan Medical School, Ann Arbor.
Raymond A JeanDepartment of Surgery, University of Michigan Medical School, Ann Arbor.
Dana A TelemDepartment of Surgery, University of Michigan Medical School, Ann Arbor.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Wide variation exists in how surgeons approach the repair of emergent presentation of ventral hernias, with many opting to avoid mesh in the acute setting. The long-term recurrence rates after emergent hernia repair and the effects of mesh on safety and recurrence remain poorly characterized. Objective: To evaluate the long-term reoperation rate for recurrence and safety of mesh use after emergent ventral hernia repair. Design, Setting, and Participants: This retrospective cross-sectional study of adults aged 18 years or older who underwent emergent inpatient ventral hernia repair used 100% Medicare administrative claims data from January 1, 2011, to December 31, 2021. Patients were followed up through death or termination of Medicare insurance. The data analysis was conducted between April and December 2024. Exposures: Open hernia repair with or without mesh use and with or without enterectomy. Main Outcomes and Measures: The primary outcome was the reoperation rate for recurrence after open emergent hernia repair stratified by mesh use. The secondary outcome was mesh explantation rates for emergent open repairs performed with and without enterectomy. The time-to-event analysis used Royston-Parmar models. Results: A total of 122 651 adult Medicare beneficiaries (mean [SD] age, 71.4 [21.0] years; 71 463 females [58.3%]) underwent emergent ventral hernia repair from 2011 to 2021. The median time to the follow-up event after the index hernia surgery was 3.2 years (IQR, 1.1-6.0 years). The 10-year reoperation rate for recurrence after emergency ventral hernia repair was 16.3% (95% CI, 15.9%-16.6%). Among emergent open repairs, 30 922 (30.0%) were repaired with mesh. Of those undergoing emergent open repairs with enterectomy, 2055 patients (18.2%) received mesh. Overall, patients repaired with mesh had significantly lower 10-year recurrence rates than those repaired without mesh (13.0% [95% CI, 13.0%-13.8%] vs 18.9% [18.4%-18.9%]; hazard ratio [HR], 0.66 [95% CI, 0.63-0.69]; P < .001). Mesh explantation rates up to 10 years after surgery were not significantly different between emergent open repairs that did and did not require enterectomy (3.8% [95% CI, 2.8%-4.8%] vs 3.2% [95% CI, 2.9%-3.4%]; HR, 1.20 [95% CI, 0.91-1.59]). Conclusions and Relevance: In this cross-sectional study of patients undergoing emergent open hernia repairs, mesh use was associated with decreased risk of recurrence and was not associated with increased risk of mesh explantation in the setting of enterectomy. This study suggests that surgeons may consider more consistent use of mesh in the emergent setting to possibly improve long-term outcomes.

Indexed as

Hernia, VentralHerniorrhaphyReoperationSurgical MeshAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMedicareMiddle AgedRecurrenceRetrospective StudiesUnited States

Identifiers

PMID41252167
PMCPMC12628106

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.