ReviewMolecular and cellular biochemistry2026
Mechanostimulation of neuroendocrine cells and their clinical relevance.
Review in Molecular and cellular biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Mechanosensitive channels uniquely convert mechanical stimuli like pressure or stretch into electrochemical signals. They largely function as ion channels that create changes in electrochemical gradients across membranes. Mammals express a variety of mechanosensitive channels including piezo and transient receptor potential family members that have demonstrated essential functions in excitable tissues. Although the role of mechanosensitive channels has become well established in nervous tissues, the role of these channels in other excitable tissues is only now becoming apparent. Neuroendocrine cells are similarly excitable tissue but also have the endocrine-specific ability to produce and secrete hormones. Here, we summarize the typical function of various neuroendocrine cells while highlighting the roles of mechanosensitive channels in each with further elaboration of their clinical and functional uses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.