Evidence map›Paper›PMID 41252035›Full record

ReviewAdvances in experimental medicine and biology2026

Long-Term Health Outcomes of Children Born After In Vitro Fertilization (IVF): A Narrative Review.

Anastasia-Evanthia Kouklamani-Giannouli, Evangelia Pratsoli, Theodoros N Sergentanis, Artemis K Tsitsika

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anastasia-Evanthia Kouklamani-Giannouli"Strategies of Developmental and Adolescent Health", 2nd Department of Pediatrics, "P. & A. Kyriakou" Children's Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Evangelia Pratsoli"Strategies of Developmental and Adolescent Health", 2nd Department of Pediatrics, "P. & A. Kyriakou" Children's Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Theodoros N SergentanisDepartment of Public Health Policy, School of Public Health, University of West Attica, Athens, Greece.
Artemis K Tsitsika"Strategies of Developmental and Adolescent Health", 2nd Department of Pediatrics, "P. & A. Kyriakou" Children's Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece. info@youth-health.gr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this narrative review is to present long-term health outcomes of children conceived after in vitro fertilization (IVF). The narrative synthesis has mainly been based on systematic reviews/meta-analyses and cohort studies. Various effects were examined, spanning the neurodevelopment, cardiovascular function and metabolism, respiratory system, malignancies, reproductive health, gastrointestinal system, and endocrine glands. As a rule, children born after IVF, when restricted to singletons and cryopreservation of embryos is avoided, did not face a significant risk to the most health conditions versus their spontaneously conceived peers. However, some higher risks concerning neurodevelopment, cardiovascular function, metabolism, and allergies have been noted. Given the limited data despite the popularity of IVF, more investigation and continuous surveillance in adulthood of this group are imperative.

Indexed as

Fertilization in VitroChildChild HealthFemaleHealth StatusHumansInfant, NewbornMalePregnancyInfertilityIn Vitro Fertilization (IVF)Long-term healthMorbidityRisk factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.