Evidence map›Paper›PMID 41252028›Full record

ArticleAdvances in experimental medicine and biology2026

A Rule-Based System for Condition-Specific Recommendations and Sentiment Classification Using Machine Learning and Deep Learning after the Application of a Semantic-Based Sentiment Analysis Methodology on the UCI Drug Reviews Dataset.

Chrysoula P Bourtzinakou

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Article in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

1 author.

Chrysoula P BourtzinakouIonian University, Corfu, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents a comprehensive analysis of the UCI drug reviews dataset, focusing on generating condition-specific drug recommendations and utilizing machine learning and deep learning techniques for sentiment classification. A healthcare-specific semantic filtering methodology is introduced to address the challenges posed by medical terminology in sentiment analysis, including a rule- based approach to filter condition-related terms. The sentiment analysis employs the VADER sentiment analyzer, enhanced with custom medical lexicons. Additionally, a custom measure was developed to incorporate sentiment scores, review ratings, and social validation metrics, providing targeted drug recommendations based on specific conditions.We applied both machine learning and deep learning models, including Bidirectional Long Short-Term Memory (Bi-LSTM) networks, to predict sentiment across drug reviews. The Bi-LSTM model, enhanced by an Embedding layer, was designed to capture long-range word dependencies, achieving an accuracy of 81.89%. Furthermore, CNN-Bidirectional LSTM models were explored using pretrained Word2Vec and GloVe embeddings, which increased accuracy to 89.94%.The findings offer valuable insights into patient experiences with various drugs and demonstrate the effectiveness of deep learning models in capturing the nuanced context of patient reviews. Future work will focus on expanding this methodology to real-time data sources, further enhancing predictive accuracy and relevance.

Indexed as

Deep LearningMachine LearningSemanticsDatabases, FactualHumansBi-LSTMCNNCondition-specific recommendationsLSTMSemantic filteringSentiment analysisTF-IDFWord2Vec

Identifiers

PMID41252028

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.