Evidence map›Paper›PMID 41251999›Full record

ReviewAdvances in experimental medicine and biology2026

Towards More Effective Treatments in Stroke-Induced Aphasia: A Discussion of the Evolution of Treatment Programs.

Eugenia Savvidou, Lambros Messinis, Grigorios Nasios, Panayiotis Patrikelis, Nikolaos Grigoriadis

Abstract readReview
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In one paragraph

Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eugenia SavvidouLaboratory of Neuropsychology and Behavioural Neuroscience, School of Psychology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Lambros MessinisLaboratory of Neuropsychology and Behavioural Neuroscience, School of Psychology, Aristotle University of Thessaloniki, Thessaloniki, Greece. lmessinis@psy.auth.gr.
Grigorios NasiosDepartment of Speech and Language Therapy, School of Health Sciences, University of Ioannina, Ioannina, Greece.
Panayiotis PatrikelisLaboratory of Neuropsychology and Behavioural Neuroscience, School of Psychology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Nikolaos GrigoriadisThe Multiple Sclerosis Center, 2nd Department of Neurology, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

THEORETICAL

backgroundAs the number of patients with post-stroke aphasia continues to rise, the need for implementing effective rehabilitation interventions that can comprehensively address the complex clinical, cognitive, and linguistic profile of patients with aphasia (PWA) becomes mandatory.

objectiveThe purpose of this review paper is to systematize the existing literature concerning the multiple rehabilitation interventions that target linguistic and non-linguistic deficits of PWA.

methodOur article provides a narrative review, comprised of English language articles retrieved from academic databases, such as PubMed, SpringerLink, and ScienceDirect. The search period spans from January 1990 to April 2024.

resultsThe categorization of non-linguistic interventions in post-stroke PWA follows three distinct pathways. One line of research focuses on cognitive training of specific cognitive domains, the other focuses on more comprehensive rehabilitation paradigms, while the third combines typical Speech Language Therapy (SLT) with non-linguistic cognitive rehabilitation interventions.

conclusionGiven the complexity of clinical manifestations of aphasia, the multifaceted cognitive profile of PWA, as well as the methodological variation of the research dedicated to rehabilitation interventions, the answer to the question of intervention effectiveness remains elusive.

Indexed as

AphasiaStrokeStroke RehabilitationCognitionHumansLanguage TherapySpeech TherapyTreatment OutcomeCognitive trainingCombined trainingPost-stroke aphasiaRehabilitation

Identifiers

PMID41251999

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.