ArticleTropical animal health and production2025
Analysis of insertion/deletion variation of litter size in Guizhou black goat.
Article in Tropical animal health and production, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study aimed to explore the genetic differences between high-litter size (HL) and low-litter size (LL) groups of Guizhou black goat, focusing on InDel variations and their potential association with reproductive traits.
methodsWhole-genome resequencing was performed on goats from the HL and LL groups to identify InDel variants. Selection signal analysis was conducted using F
resultsPrincipal component analysis and phylogenetic tree construction revealed clear genetic differentiation between HL and LL groups based on InDel variation. A total of 24 candidate genes potentially related to litter size were identified. Functional enrichment analysis also enriched for functions related to reproduction.
conclusionThe identified candidate genes and enriched pathways offer new insights into the genetic architecture underlying reproductive performance and present potential targets for marker-assisted selection in goat breeding.
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