Evidence map›Paper›PMID 41251881›Full record

ArticleCurrent microbiology2025

Anticancer Activity of Endophytic Bacterial Extracts from Potentilla supina in HepG2 and HCT116 Cells.

Xia Li, Xinxin Zhao, Jinqiu Gui, Yuling Liu, Guiru Kong

Abstract read
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In one paragraph

Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xia LiDepartment of Pathogen Biology, Mudanjiang Medical University, No. 3 Tongxiang Road, Mudanjiang, 157011, Heilongjiang, China. lixia@mdjmu.edu.cn.ORCID http://orcid.org/0009-0000-2835-6875
Xinxin ZhaoDepartment of Pathogen Biology, Mudanjiang Medical University, No. 3 Tongxiang Road, Mudanjiang, 157011, Heilongjiang, China.
Jinqiu GuiDepartment of Pathogen Biology, Mudanjiang Medical University, No. 3 Tongxiang Road, Mudanjiang, 157011, Heilongjiang, China.
Yuling LiuDepartment of Pathogen Biology, Mudanjiang Medical University, No. 3 Tongxiang Road, Mudanjiang, 157011, Heilongjiang, China.
Guiru KongDepartment of Pathogen Biology, Mudanjiang Medical University, No. 3 Tongxiang Road, Mudanjiang, 157011, Heilongjiang, China.

Funding

Department of Education, Heilongjiang Province 2023‒KYYWFMY‒0026
6 · The paper itself

Abstract

Endophytes in plant tissues produce diverse secondary metabolites, which hold promise for the development of new anticancer drugs. This study aimed to isolate endophytic bacteria from Potentilla supina and evaluate their anticancer activities. Seventy-two endophytic bacterial strains were isolated from P. supina, followed by fermentation and ethyl acetate extraction to prepare seventy-two strain extracts. The antiproliferative activity of these extracts against HepG2 and HCT116 cells was assessed using the MTT assay. Ultimately, high-activity strain J14 was screened out based on IC

Indexed as

Antineoplastic AgentsBacillusBacteriaEndophytesPotentillaBacterial LysatesCell ProliferationHCT116 CellsHep G2 CellsHumansRNA, Ribosomal, 16SAntineoplastic AgentsBacterial LysatesRNA, Ribosomal, 16S

Identifiers

PMID41251881

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.