Evidence map›Paper›PMID 41251852›Full record

ReviewArchives of microbiology2025

Bentonite clay in aflatoxin mitigation: advances, efficiency and perspectives.

Syed Ali Raza Naqvi, Muhammad Kaleem Khan Khosa, Ameer Fawad Zahoor, Matloob Ahmad, Ariba Abdullah, Muhammad Ramzan Saeed Ashraf Janjua, Syed Ansar Abidi, Fatma Mohamed Ameen Khalil, Mohamed Fawzy Ramadan, João Miguel Rocha

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Syed Ali Raza NaqviDepartment of Chemistry, Government College University Faisalabad, Faisalabad, 38000, Pakistan. draliraza@gcuf.edu.pk.
Muhammad Kaleem Khan KhosaDepartment of Chemistry, Government College University Faisalabad, Faisalabad, 38000, Pakistan.
Ameer Fawad ZahoorDepartment of Chemistry, Government College University Faisalabad, Faisalabad, 38000, Pakistan.
Matloob AhmadDepartment of Chemistry, Government College University Faisalabad, Faisalabad, 38000, Pakistan.
Ariba AbdullahDepartment of Chemistry, Government College University Faisalabad, Faisalabad, 38000, Pakistan.
Muhammad Ramzan Saeed Ashraf JanjuaDepartment of Chemistry, Government College University Faisalabad, Faisalabad, 38000, Pakistan.
Syed Ansar AbidiPhoenix Chemicals Private Limited, 33-Lahore Sheikhupura Road, Sheikhupura, Pakistan.
Fatma Mohamed Ameen KhalilApplied College, Unit of Health Specialties, Basic Sciences and Their Applications, King Khalid University, Mohayil Asir Abha, 61421, Abha, Saudi Arabia.
Mohamed Fawzy RamadanDepartment of Clinical Nutrition, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
João Miguel RochaUniversidade Católica Portuguesa, CBQF, Centro de Biotecnologia e Química Fina, Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho 1327, 4169-005, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycotoxins, which are toxic secondary metabolites produced by fungi, contaminate a wide range of food and feed items and represent significant health concerns to both humans and animals. The most potent and widespread of these are aflatoxins (AFs), particularly Aflatoxin B1 (AFB1), which is commonly found in peanuts, cottonseed, spices, animal feed, and milk. AFB1 is linked to liver cancer, immunosuppression, reproductive problems, and growth retardation, particularly in poultry, cattle, and humans. Aflatoxin (AF) resistance to conventional detoxification treatments is frequently caused by its chemical stability and persistence - necessitating the development of more sustainable and efficient approaches. This review, which focuses on adsorption-based detoxification of AFs, looks at a variety of mitigation options, including chemical, biological, and physical procedures. Bentonite clay is unique among binders due to its high adsorption capacity, low cost, and regulatory approval from institutions such as the European Food Safety Authority (EFSA) and the European Commission (EC Regulation 1060/2013). Recent advances in bentonite clay surface modification have increased the efficacy of AF binding and enhanced the physicochemical properties of clay, which reduces the bioavailability of AFs in animal feed. The review discusses bentonite's structural features, adsorption methods, kinetic behavior, potential developments and its future prospects.

Indexed as

AflatoxinsBentoniteClayAdsorptionAnimal FeedAnimalsFood ContaminationHumansAflatoxinsBentoniteClayAFsAnimal feedBentonite clayBioavailabilityFood safetyFungiLivestockToxins

Identifiers

PMID41251852

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.