Evidence map›Paper›PMID 41251843›Full record

ArticleUrolithiasis2025

Ureteroscopy for stone disease in the elderly (≥ 80 years): Outcomes of a multicentre study from YAU and EAU endourology groups.

Lazaros Tzelves, Bhaskar Somani, Steffi Kar Kei Yuen, Vineet Gauhar, Smita De, Amelia Pietropaolo, Daniele Castellani, Deepak Ragoori, Esteban Emiliani, Eugenio Ventimiglia and 27 more

Abstract readMulticenter Study
In one paragraph

Article in Urolithiasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Lazaros Tzelves2nd Department of Urology, Sismanoglio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Bhaskar SomaniEAU Endourology Endourology Section, Arnhem, The Netherlands.
Steffi Kar Kei YuenEAU Endourology Endourology Section, Arnhem, The Netherlands.
Vineet GauharEAU Endourology Endourology Section, Arnhem, The Netherlands.
Smita DeDepartment of Urology, Cleveland Clinic Glickman Urological & Kidney Institute, Cleveland, OH, USA.
Amelia PietropaoloEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Daniele CastellaniEAU Endourology Endourology Section, Arnhem, The Netherlands.
Deepak RagooriDepartment of Urology, Asian Institute of Nephrology and Urology, Hyderabad, India.
Esteban EmilianiEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Eugenio VentimigliaEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Arman TsaturyanEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Tarik Emre SenerEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Maria Florencia FrascheriDepartment of Urology, University Hospitals Southampton, NHS Trust, Southampton, UK.
Alba SierraEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Francesco EspertoEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Łukasz NowakEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Vincent De ConinckEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Ioannis MykoniatisEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Alberto OliveroEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Rifat Burak ErgülEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Begoña Ballesta MartinezEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Alejandro Bautista-Perez-GavilanDepartment of Urology, Cleveland Clinic Glickman Urological & Kidney Institute, Cleveland, OH, USA.
Sahil PatelDepartment of Urology, Cleveland Clinic Glickman Urological & Kidney Institute, Cleveland, OH, USA.
Eric VillalbaDepartment of Urology, Hospital Clínic de Barcelona - University of Barcelona, Barcelona, Spain.
Qasim SeyidovDepartment of Urology, School of Medicine, Marmara University, Istanbul, Turkey.
Joren VanthoorDepartment of Urology, AZ Klina, Brasschaat, Belgium.
Stavros TsiakarasDepartment of Urology, Aristotle University of Thessaloniki, Thessaloniki, 541 24, Greece.
Panagiotis Triantafyllou2nd Department of Urology, Sismanoglio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Arianna PischetolaDepartment of Urology, Campus Bio-Medico University, Rome, Italy.
Luca VillaDivision of Experimental Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy.
Paola ArenaDepartment of Urology, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.
Øyvind UlvikEAU Endourology Endourology Section, Arnhem, The Netherlands.
Mathias S ÆsøyDepartment of Urology, University Hospital Del Vinalopó, Alicante, Spain.
Peder GjengstøDepartment of Urology, Haukeland University Hospital, Bergen, Norway.
Ali TalyshinskiiEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands.
Christian BeislandDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Patrick Juliebø-JonesEAU Young Academic Urologists (YAU) Urolithiasis and Endourology Working Group, Arnhem, The Netherlands. jonesurology@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to perform a multi-centre and global study evaluating the clinical outcomes and complications associated with of URS for stone disease in patients aged 80 years and above. Retrospective analysis was conducted on patients aged ≥ 80 years who underwent URS for stone disease between January 2014 and December 2024, across 20 centres in 14 countries. A total of 679 patients aged ≥ 80 years underwent ureteroscopy (URS), with a median age of 83 years (IQR 81–86) and a male-to-female ratio of 1.2:1. Most patients were ASA grade 2 (52%) and presented electively (95%), with general anaesthesia used in 77% of cases. The median cumulative stone size was 11 mm (IQR 7–15), and 56% had a single stone. The overall stone-free rate (SFR) was 70% for zero fragments, increasing to 84% when including fragments ≤ 2 mm, and 90% when including fragments ≤ 4 mm. The overall 30-day complication rate was 16%, with major complications (Clavien-Dindo grade ≥ 3) in 2.8% of patients. The most common complication was urinary tract infection (9.4%). One procedure-related death (0.1%) was recorded. Multivariable analysis identified ASA score ≥ 3 (OR 1.60), operative time > 60 min (OR 1.73), and emergency surgery (OR 2.96) as independent predictors of complications. Ureteroscopy can be performed in patients aged 80 years and above with a low risk of major complications and acceptable stone clearance rates. Avoiding both emergency surgery and prolonged operative times can help reduce the morbidity profile.

Indexed as

Kidney CalculiPostoperative ComplicationsUreteral CalculiUreteroscopyAged, 80 and overFemaleHumansMaleRetrospective StudiesTreatment OutcomeComplicationsElderlyMortalityOlderUreteroscopyUrolithiasis

Identifiers

PMID41251843
PMCPMC12627142

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.