Evidence map›Paper›PMID 41251809›Full record

ArticleMetabolic brain disease2025

Evaluation of the antidepressant potential of Duloxetine, Coffea canephora, and Nigella sativa in a rat depression model.

Enas S Abdel-Baky, Shadia A Radwan, Faten Mohamed Abdelhamid, Omnia N Abdelrhman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolic brain disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Enas S Abdel-BakyDepartment of Biological and Geological Sciences, Faculty of Education, Ain Shams University, Cairo, Egypt.
Shadia A RadwanDepartment of Biological and Geological Sciences, Faculty of Education, Ain Shams University, Cairo, Egypt.
Faten Mohamed AbdelhamidDepartment of Biological and Geological Sciences, Faculty of Education, Ain Shams University, Cairo, Egypt. fatenmohamed@edu.asu.edu.e.g.
Omnia N AbdelrhmanDepartment of Biological and Geological Sciences, Faculty of Education, Ain Shams University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is a complex disorder involving neurotransmitter imbalance, oxidative stress, and inflammation of the brain tissue. Traditional antidepressants like duloxetine (Cymbalta

Indexed as

Antidepressive AgentsCoffeaDepressionDuloxetine HydrochlorideNigella sativaPlant ExtractsAnimalsBehavior, AnimalDisease Models, AnimalMaleOxidative StressRatsRats, WistarReserpineAntidepressive AgentsDuloxetine HydrochloridePlant ExtractsReserpineBlack seedsDepressionDuloxetineGreen coffeeReserpine

Identifiers

PMID41251809
PMCPMC12627154

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.