ArticlePediatric nephrology (Berlin, Germany)2026
Heart-kidney transplants linked to better outcomes compared to heart-only transplants in children with non-dialysis-dependent advanced chronic kidney disease.
Article in Pediatric nephrology (Berlin, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Update of
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic kidney disease (CKD) causes significant morbidity and mortality among children with heart failure. Although the survival benefit of a simultaneous heart-kidney transplant has been demonstrated in children with heart failure undergoing dialysis [1], the optimal intervention, simultaneous heart-kidney transplant or heart-only transplant, in those with advanced CKD but not requiring dialysis remains uncertain (Choudhry et al. Pediatr Transplant 26:e14149, 2022).
methodsUsing the Scientific Registry of Transplant Recipients (SRTR), we identified all pediatric heart transplant recipients (age ≤ 18 years) who were transplanted between 1989 and 2022 with an estimated glomerular filtration rate (eGFR) of less than 45 mL/min/1.73 m
resultsWe observed significantly higher patient survival (HR: 0.29; 95% CI: 0.1-0.81; p = 0.02) and heart graft survival (HR: 0.24; 95% CI: 0.08-0.67; p = 0.002) in simultaneous heart-kidney recipients compared to propensity-score-weighted heart-only recipients.
conclusionsIn children awaiting a heart transplant with advanced non-dialysis-dependent CKD (eGFR < 45 ml/min/1.73 m
Indexed as
Identifiers
41251792What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.