Evidence map›Paper›PMID 41251641›Full record

ArticleJACC. Case reports2026

Radiofrequency Ablation and Right Purkinje De-Networking for Moderator Band PVC-Induced VF: Broadening the Therapeutic Landscape.

Eduardo Sanhueza, Matthew Hanson, Victor Neira, Sanoj Chacko, Andres Enriquez, Jacob Pardy, David Bakker, Roji Oli, Mariana Saramago, Cengiz Burak

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eduardo SanhuezaDivision of Cardiology, Queen's University, Kingston, Ontario, Canada. Electronic address: 19ejsg@queensu.ca.
Matthew HansonDivision of Cardiology, Queen's University, Kingston, Ontario, Canada.
Victor NeiraDivision of Cardiology, Queen's University, Kingston, Ontario, Canada.
Sanoj ChackoDivision of Cardiology, Queen's University, Kingston, Ontario, Canada.
Andres EnriquezDivision of Cardiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jacob PardyAbbott, Chicago, Illinois, USA.
David BakkerDivision of Cardiology, Queen's University, Kingston, Ontario, Canada.
Roji OliDivision of Cardiology, Queen's University, Kingston, Ontario, Canada.
Mariana SaramagoDivision of Cardiology, Queen's University, Kingston, Ontario, Canada.
Cengiz BurakDivision of Cardiology, Queen's University, Kingston, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdiopathic ventricular fibrillation (VF) can occasionally be triggered by rare premature ventricular complexes (PVCs), including those from the moderator band. Radiofrequency ablation (RFA) is challenging given low PVC burden and anatomic complexity. CASE SUMMARY: A 36-year-old man with idiopathic VF and an implantable cardioverter-defibrillator for secondary prevention presented with multiple shocks. The VF episodes were triggered by short-coupled PVCs from the moderator band. Despite a low PVC burden (<1%), zero-fluoroscopy catheter ablation was performed. RFA was guided by pace mapping, followed by right-sided Purkinje de-networking. The procedure was uncomplicated, and at 8-month follow-up, the patient remained asymptomatic, with no PVCs or arrhythmic events. DISCUSSION: Low-burden PVC-triggered VF is challenging, as conventional pace mapping is limited. Targeted Purkinje network ablation (de-networking) appears to reduce the risk of recurrent VF. TAKE-HOME-MESSAGE: Pace-mapped RFA combined with ipsilateral Purkinje de-networking may be an effective zero-fluoroscopy strategy for PVC-induced VF, even with low ectopic burden.

Indexed as

cardiac ablationelectrophysiologypremature ventricular complexPurkinje networkradiofrequency ablationventricular fibrillation

Identifiers

PMID41251641
PMCPMC12926088

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.