Evidence map›Paper›PMID 41251383›Full record

ArticleJournal of the American Chemical Society2025

Experimental Evidence for Radical-Polar Crossover in Competition with, Rather Than Preceding, Alkene Formation by Microbial Ethylene-Forming Enzyme.

Evan J Burke, Chao Wang, Holly Lussier, Elvira R Sayfutyarova, Alexey Silakov, Carsten Krebs, J Martin Bollinger, Jeffrey W Slater

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Evan J BurkeDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0003-3335-6444
Chao WangDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0001-5664-2350
Holly LussierDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Elvira R SayfutyarovaDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0001-8403-5013
Alexey SilakovDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Carsten KrebsDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0002-3302-7053
J Martin BollingerDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0003-0751-8585
Jeffrey W SlaterDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0002-1126-8905

Funding

The role of geometric structure in avoidance of oxygen rebound to enable aliphatic halogenation and oxacyclization by non-heme Fe(IV)-oxo (ferryl) complexesR01GM141284 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI SILAKOV, ALEXEY · 2022 to 2025
$1.5M
Interrogating the Haloferryl State of Iron(II)- and 2-Oxoglutarate-Dependent Halogenases through Mimicry and Active Site ModificationsF32GM136156 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI SLATER, JEFFREY WORTHINGTON · 2020 to 2022
$201k
NIGMS NIH HHS F32 GM136156NIGMS NIH HHS R01 GM141284
6 · The paper itself

Abstract

Ethylene-forming enzyme (EFE) catalyzes a reaction that sets it apart from other iron(II)- and 2-oxoglutarate-dependent (Fe/2OG) oxygenases. In this reaction, all four oxidizing equivalents of O

Indexed as

AlkenesEthylenesFree RadicalsLyasesOxidation-ReductionAlkenesethyleneethylene forming enzymeEthylenesFree RadicalsLyases

Identifiers

PMID41251383
PMCPMC12820722

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.