ArticleInfection and immunity2025
A zinc-free alternative ribosomal protein RpsN.2 confers survival advantage to group A streptococcus during Zn scarcity.
Article in Infection and immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Article
- AdcBC-dependent zinc uptake influences physiological responses inJournal of oral microbiology · 2026Article
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Authors and funding
6 authors.
Funding
Abstract
Infection induces unfavorable environments in the host that can be detrimental to the survival of commensal and pathogenic bacteria. Although the adaptive strategies employed by pathogenic bacteria to overcome harsh environments are characterized, similar capabilities of the commensal bacteria to survive in hostile host niches during infection remain understudied. The human oral pathogen group A streptococcus (GAS) encounters host-induced zinc (Zn) limitation at infection sites that limits bacterial proliferation. However, GAS employs the Zn-sensing transcription regulator AdcR to monitor Zn levels and evades host-imposed Zn scarcity by upregulating the AdcR regulon. To elucidate the adaptive responses of oropharyngeal commensal streptococci to Zn scarcity, we analyzed the oropharyngeal pathogenic and commensal streptococcal genomes for the presence of the AdcR regulon. GAS has the full repertoire of the AdcR regulon that includes
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