Evidence map›Paper›PMID 41251370›Full record

ArticleAntimicrobial agents and chemotherapy2025

Pharmacokinetic modeling and efficacy of ceftobiprole medocaril against pneumonic tularemia in cynomolgus macaques.

Mark M Hahn, Michael S Anderson, Matthew Snyder, Wantong Du, Ying-Liang Chou, Brent McCracken, Jennifer I Smart, Karine Litherland, Stephen Keech, Franziska von Siebenthal and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mark M HahnBattelle, West Jefferson, Ohio, USA.ORCID 0000-0002-4955-7497
Michael S AndersonBattelle, West Jefferson, Ohio, USA.ORCID 0000-0001-9624-6344
Matthew SnyderBattelle, West Jefferson, Ohio, USA.ORCID 0000-0002-0881-8507
Wantong DuBattelle, West Jefferson, Ohio, USA.
Ying-Liang ChouBattelle, West Jefferson, Ohio, USA.
Brent McCrackenBattelle, West Jefferson, Ohio, USA.
Jennifer I SmartBasilea Pharmaceutica International Ltd, Allschwil, Switzerland.ORCID 0000-0002-4310-6599
Karine LitherlandBasilea Pharmaceutica International Ltd, Allschwil, Switzerland.ORCID 0009-0000-8243-0482
Stephen KeechBasilea Pharmaceutica International Ltd, Allschwil, Switzerland.
Franziska von SiebenthalBasilea Pharmaceutica International Ltd, Allschwil, Switzerland.
Mark JonesBasilea Pharmaceutica International Ltd, Allschwil, Switzerland.
Lisa N HenningBattelle, West Jefferson, Ohio, USA.

Funding

Basilea PharmaceuticaU.S. Department of Health and Human Services HHSO100201600002C
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsCephalosporinsFrancisella tularensisTularemiaAnimalsDisease Models, AnimalFemaleMacaca fascicularisMaleMicrobial Sensitivity TestsAnti-Bacterial Agentsceftobiprole medocarilCephalosporinsbiodefense and biothreat preparednessceftobiprole medocarilFrancisella tularensispharmacokinetic modelingpneumonic tularemiapreclinical models

Identifiers

PMID41251370
PMCPMC12691666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.