Evidence map›Paper›PMID 41251367›Full record

ArticleAntimicrobial agents and chemotherapy2025

Selective antimicrobial photodynamic therapy of clinical isolates from patients with infected diabetic foot ulcers using a small cationic chlorin.

Anita S Amorim, Chloe M Hobbs, Zoe A Arnaut, Mariette M Pereira, David Gallagher, Teck Wee Boo, Georgina Gethin, James P O'Gara, Luis G Arnaut

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anita S Amorim *Chemistry Department, CQC-IMS, University of Coimbra, Coimbra, Portugal.ORCID 0000-0002-9651-2232
Chloe M Hobbs *Microbiology, School of Biological and Chemical Sciences, University of Galway, Galway, Ireland.ORCID 0009-0008-5087-5020
Zoe A ArnautChemistry Department, CQC-IMS, University of Coimbra, Coimbra, Portugal.ORCID 0000-0002-2364-295X
Mariette M PereiraChemistry Department, CQC-IMS, University of Coimbra, Coimbra, Portugal.ORCID 0000-0003-4958-7677
David GallagherSchool of Medicine, University of Galway, Galway, Ireland.
Teck Wee BooSchool of Medicine, University of Galway, Galway, Ireland.
Georgina GethinSchool of Nursing and Midwifery, University of Galway, Galway, Ireland.
James P O'GaraMicrobiology, School of Biological and Chemical Sciences, University of Galway, Galway, Ireland.ORCID 0000-0003-3866-7161
Luis G ArnautChemistry Department, CQC-IMS, University of Coimbra, Coimbra, Portugal.ORCID 0000-0002-3223-4819

Funding

Fundação para a Ciência e a Tecnologia PTDC/QUI-OUT/0303/2021Health Research Board CDA-2019-007
6 · The paper itself

Abstract

Diabetic foot ulcers (DFUs) are a major complication of diabetes mellitus and the principal factor contributing to lower limb amputations. Antimicrobial photodynamic therapy (aPDT) is a promising therapeutic strategy because it is not limited by drug resistance. A new photosensitizer, a low molecular weight dicationic imidazolyl chlorin (IC-H-Me

Indexed as

Anti-Bacterial AgentsDiabetic FootPhotochemotherapyPhotosensitizing AgentsPorphyrinsBiofilmsHumansMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsPotassium IodidePseudomonas aeruginosaStaphylococcus epidermidisAnti-Bacterial AgentschlorinPhotosensitizing AgentsPorphyrinsPotassium Iodideantimicrobial resistancebiofilmsdiabetic foot ulcersinfectionphotodynamic inactivation

Identifiers

PMID41251367
PMCPMC12691672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.