Trial reportJournal of pediatric gastroenterology and nutrition2026
Efficacy of low volume transanal irrigation in children with retentive fecal incontinence: A randomized controlled trial.
Trial report in Journal of pediatric gastroenterology and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05570318 (Effect of MiniGo As Add-on to Oral Laxatives for Children with Constipation and Fecal Incontinence), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of MiniGo As Add-on to Oral Laxatives for Children with Constipation and Fecal Incontinence
Who cites it
1 citing paper in PubMed.
- Efficacy of low volume transanal irrigation in children with retentive fecal incontinence: A randomized controlled trial.Journal of pediatric gastroenterology and nutrition · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectivesTo assess whether low-volume transanal irrigation (L-TAI) is effective as add-on to oral laxative therapy for children with functional constipation and retentive fecal incontinence.
methodsTwo-arm randomized controlled trial, including children aged 4-14 suffering from retentive fecal incontinence. All included children were refractory to at least 2 months treatment with stool softening oral laxatives. Children were included across three pediatric departments in Denmark and randomized into two treatment groups. Treatment duration was 6 weeks. The control group continued oral laxative therapy. The intervention group received L-TAI as add-on. The primary objective was evaluating reduction in fecal incontinence episodes. Secondary objectives included assessment of constipation symptoms, rectal diameter, and well-being based on the WHO-5 questionnaire. Participants were classified as nonresponders (0%-49% reduction) or responders (partial response = 50%-99% reduction, or full response = 100% reduction).
resultsFifty children were included. The respective median ages were 7 (interquartile range [IQR] = 3) in the intervention group and 6 years (IQR = 1) in the control group. In the intervention group, 75% were responders with 35% experiencing full response, while 33% in the control group were responders, with 4.8% experiencing full response (p = 0.007 and p = 0.020 for response and full response respectively). At follow-up, 55% of the intervention group and 90.5% of the control group still met ROME-IV criteria for constipation (p = 0.010).
conclusionsL-TAI is effective as add-on to oral laxatives in treating fecal incontinence and constipation. Further studies with longer follow-up periods are needed to assess long-term effects. Clinical Trial identification number: NCT05570318 (https://clinicaltrials.gov/study/NCT05570318).
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