ArticleJournal of cardiovascular electrophysiology2025
Efficacy of Peak Frequency in Pulmonary Vein Isolation Using Pulsed Field Ablation for Atrial Fibrillation.
Article in Journal of cardiovascular electrophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Efficacy of Peak Frequency in Pulmonary Vein Isolation Using Pulsed Field Ablation for Atrial Fibrillation.Journal of cardiovascular electrophysiology · 2025Article
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Authors and funding
9 authors.
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Abstract
introductionCatheter ablation technology for atrial fibrillation (AF) has been improving annually, and pulsed field ablation (PFA) has recently become possible. The optimal protocol has yet to be elucidated, and considering variables, including catheter contact force, is essential for conducting more effective and safer ablation. This study was conducted using peak frequency (PF) mapping to analyze the catheter tip electrode frequency during PFA under the hypothesis that higher PF shows stronger myocardial contact and yields a more pronounced electrical current effect.
methodsBetween December 2024 and April 2025, 12 consecutive patients who underwent PFA for paroxysmal AF using the FARAPULSE system at our hospital were included in this study. Overall, 180 applications were analyzed. The PF before energy delivery was analyzed in the group in which the tip electrode potential disappeared following the first energy delivery using the flower-type configuration.
resultsThe PF of the distal electrode in the group with potential disappearance following the first delivery was significantly higher than it was in the group without disappearance (291 ± 88 Hz vs. 267 ± 70 Hz, p = 0.02). When the potential at the tip electrode ranged from 0.5 to 1.5 mV, the area under the curve was 0.73. At a cutoff value of 261 Hz for peak frequency, sensitivity reached 67%, and specificity reached 60%.
conclusionEffective PFA may be achieved using the frequency of the catheter tip electrode as an index. Delivering energy to myocardial regions with higher PF may yield greater ablation efficacy.
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