SynthesisDiabetes, obesity & metabolism2026
Effects of hypoxic training interventions on cardiometabolic health of adults with overweight and obesity: A systematic review and meta-analysis.
Synthesis in Diabetes, obesity & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of hypoxic training interventions on cardiometabolic health of adults with overweight and obesity: A systematic review and meta-analysis.Diabetes, obesity & metabolism · 2026Pooled it
- Correction to "Effects of Hypoxic Training Interventions on Cardiometabolic Health of Adults With Overweight and Obesity: A Systematic Review and Meta-Analysis".Diabetes, obesity & metabolism · 2026Article
- Exercise in Hypoxic Environments: An Overview of Systematic Reviews on Performance, Physiological Adaptation, and Clinical Implications.Sports (Basel, Switzerland) · 2026Review
- Combining exercise and hypoxia for brain health: from elite athlete altitude training camps to clinical applications.AIMS neuroscience · 2026Review
Corrections and comments
- Erratum issued
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity rates have surpassed underweight globally, increasing the burden of cardiometabolic complications on healthcare systems. Hypoxic training has emerged as a potential intervention to improve cardiometabolic health in adults with obesity, but evidence remains inconclusive. This systematic review and meta-analysis evaluated whether hypoxic training is more effective than normoxic training in this context. A systematic search of PubMed, Web of Science, and Cochrane Library (up to June 2025) identified randomised controlled trials comparing hypoxic and normoxic training in adults with overweight or obesity. Outcomes included glucose homeostasis, lipid profile, and blood pressure. Subgroup, moderation, and sensitivity analyses were also conducted to explore sources of heterogeneity and assess the robustness of findings. Of 1815 studies screened, 9 (278 participants) met the criteria. Meta-analysis results demonstrated no significant differences between hypoxic and normoxic training for fasting glucose (p = 0.118) or fasting insulin (p = 0.415), with substantial heterogeneity observed across studies (I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.